CRCGN008_HEPG2_24H:N01 Gene Set
Genes
56 genes differentially expressed following the CRCGN008_HEPG2_24H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
6.3406
|
|
LCN2
|
lipocalin 2
|
5.6149
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
5.4286
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.4038
|
|
CBR3
|
carbonyl reductase 3
|
5.3956
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.66275
|
|
MYLK
|
myosin light chain kinase
|
4.66275
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.60315
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.49295
|
|
EGF
|
epidermal growth factor
|
4.3005
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.0128
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.99275
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.67572
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.39135
|
|
MAP7
|
microtubule-associated protein 7
|
3.18222
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.1755
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.1441
|
|
NMU
|
neuromedin U
|
3.01115
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.87162
|
|
ZNF589
|
zinc finger protein 589
|
2.61995
|
|
SIRT3
|
sirtuin 3
|
2.55422
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.53545
|
|
USP6NL
|
USP6 N-terminal like
|
2.50485
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.48047
|
|
CYCS
|
cytochrome c, somatic
|
2.4334
|
|
CCNA1
|
cyclin A1
|
2.1743
|
|
CSK
|
c-src tyrosine kinase
|
2.1534
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.1461
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.12795
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.09126
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
2.02385
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.0003
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.92165
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.81395
|
|
LDHD
|
lactate dehydrogenase D
|
-4.7549
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.5173
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.35975
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.04895
|
|
SPAG4
|
sperm associated antigen 4
|
-3.50045
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.331
|
|
NVL
|
nuclear VCP-like
|
-3.18035
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.89125
|
|
RPF1
|
ribosome production factor 1 homolog (S. cerevisiae)
|
-2.8509
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.68918
|
|
CDC25B
|
cell division cycle 25B
|
-2.67045
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.38943
|
|
WDR3
|
WD repeat domain 3
|
-2.3307
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.24115
|
|
RBM34
|
RNA binding motif protein 34
|
-2.1971
|
|
RNF13
|
ring finger protein 13
|
-2.13933
|
|
HTN3
|
histatin 3
|
-2.13385
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.11495
|
|
ZNF175
|
zinc finger protein 175
|
-2.1107
|
|
CCNH
|
cyclin H
|
-2.0735
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
-2.03005
|
|
IL1B
|
interleukin 1, beta
|
-2.00032
|
