| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1,1-dichloroethane 19.3 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
143 genes differentially expressed following the CRCGN008_HEPG2_24H:N02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 8.1188 |
| ADRB2 | adrenoceptor beta 2, surface | 6.2674 |
| GPATCH8 | G patch domain containing 8 | 6.03575 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.98795 |
| RPL39L | ribosomal protein L39-like | 5.547 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.47045 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 5.4063 |
| LCN2 | lipocalin 2 | 5.31085 |
| CBR3 | carbonyl reductase 3 | 5.2914 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.20915 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 5.16333 |
| MYLK | myosin light chain kinase | 5.11825 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.01935 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.93465 |
| MAMLD1 | mastermind-like domain containing 1 | 4.6941 |
| UBQLN2 | ubiquilin 2 | 4.68005 |
| PRR15L | proline rich 15-like | 4.53525 |
| KLHL21 | kelch-like family member 21 | 4.292 |
| NMU | neuromedin U | 4.27745 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.08135 |
| ARL4C | ADP-ribosylation factor-like 4C | 3.9634 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.7263 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.64805 |
| FCHO1 | FCH domain only 1 | 3.5378 |
| BAX | BCL2-associated X protein | 3.45245 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.38822 |
| MAP7 | microtubule-associated protein 7 | 3.19528 |
| STK16 | serine/threonine kinase 16 | 3.1173 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.85755 |
| CHN1 | chimerin 1 | 2.7732 |
| STIM1 | stromal interaction molecule 1 | 2.6494 |
| SIRT3 | sirtuin 3 | 2.61253 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 2.49693 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.4842 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.46375 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 | 2.4578 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 | 2.4431 |
| TBC1D10C | TBC1 domain family, member 10C | 2.4401 |
| RGSL1 | regulator of G-protein signaling like 1 | 2.42235 |
| CTC1 | CTS telomere maintenance complex component 1 | 2.3856 |
| CRTAP | cartilage associated protein | 2.3804 |
| PIH1D1 | PIH1 domain containing 1 | 2.35535 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 2.35295 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 2.336 |
| TRIM6-TRIM34 | TRIM6-TRIM34 readthrough | 2.3084 |
| VSNL1 | visinin-like 1 | 2.3069 |
| RRAGA | Ras-related GTP binding A | 2.30355 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.3027 |
| SH3D19 | SH3 domain containing 19 | 2.28157 |
| SNX7 | sorting nexin 7 | 2.27695 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 2.26585 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase | 2.2482 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 2.21854 |
| S100PBP | S100P binding protein | 2.2092 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | 2.17705 |
| FAM222B | family with sequence similarity 222, member B | 2.14615 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 2.14115 |
| CCL1 | chemokine (C-C motif) ligand 1 | 2.1356 |
| SNX24 | sorting nexin 24 | 2.11495 |
| JADE2 | jade family PHD finger 2 | 2.1095 |
| TBC1D12 | TBC1 domain family, member 12 | 2.104 |
| TXNL4B | thioredoxin-like 4B | 2.06735 |
| CLDN15 | claudin 15 | 2.04875 |
| STAC | SH3 and cysteine rich domain | 2.0322 |
| SLC25A2 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 | 2.03115 |
| TFG | TRK-fused gene | 2.008 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.00593 |
| TRIM68 | tripartite motif containing 68 | 2.0054 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.28885 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.14565 |
| NGRN | neugrin, neurite outgrowth associated | -5.04005 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.9435 |
| ZNF586 | zinc finger protein 586 | -4.9132 |
| LDHD | lactate dehydrogenase D | -4.66275 |
| TCTN1 | tectonic family member 1 | -4.47295 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.3939 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.20565 |
| CAB39 | calcium binding protein 39 | -4.10685 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.7562 |
| GNAS | GNAS complex locus | -3.65247 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.5621 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -3.5519 |
| RGS2 | regulator of G-protein signaling 2 | -3.50715 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.98005 |
| SH3GL1 | SH3-domain GRB2-like 1 | -2.8746 |
| BLCAP | bladder cancer associated protein | -2.81295 |
| REEP5 | receptor accessory protein 5 | -2.60972 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.59045 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.5816 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.57543 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -2.53505 |
| BHMT | betaine--homocysteine S-methyltransferase | -2.51405 |
| AASDHPPT | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | -2.49995 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | -2.48935 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.457 |
| ZGPAT | zinc finger, CCCH-type with G patch domain | -2.45305 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.4413 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -2.37335 |
| CDC25B | cell division cycle 25B | -2.36925 |
| GDF15 | growth differentiation factor 15 | -2.36915 |
| STXBP1 | syntaxin binding protein 1 | -2.36395 |
| LPL | lipoprotein lipase | -2.36137 |
| KCTD15 | potassium channel tetramerization domain containing 15 | -2.34505 |
| ZNF467 | zinc finger protein 467 | -2.338 |
| ZNF14 | zinc finger protein 14 | -2.33705 |
| MAPK12 | mitogen-activated protein kinase 12 | -2.3351 |
| TMEM208 | transmembrane protein 208 | -2.3073 |
| HPCA | hippocalcin | -2.29345 |
| CFP | complement factor properdin | -2.27535 |
| NOL8 | nucleolar protein 8 | -2.26635 |
| AFTPH | aftiphilin | -2.26555 |
| TBX2 | T-box 2 | -2.26085 |
| ZNF324 | zinc finger protein 324 | -2.2504 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | -2.2253 |
| TKFC | triokinase/FMN cyclase | -2.1888 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | -2.18432 |
| PDE8B | phosphodiesterase 8B | -2.15905 |
| GPR27 | G protein-coupled receptor 27 | -2.15755 |
| ZNF93 | zinc finger protein 93 | -2.14283 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | -2.1377 |
| ADORA2A | adenosine A2a receptor | -2.1257 |
| ZNF33B | zinc finger protein 33B | -2.12445 |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) | -2.1227 |
| CDHR1 | cadherin-related family member 1 | -2.12125 |
| PHACTR1 | phosphatase and actin regulator 1 | -2.10915 |
| ZNF580 | zinc finger protein 580 | -2.0986 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) | -2.09165 |
| RNF187 | ring finger protein 187 | -2.08895 |
| ABR | active BCR-related | -2.08538 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 | -2.07695 |
| CRIP2 | cysteine-rich protein 2 | -2.07345 |
| HARS1 | histidyl-tRNA synthetase 1 | -2.0575 |
| USPL1 | ubiquitin specific peptidase like 1 | -2.05005 |
| WDR91 | WD repeat domain 91 | -2.04505 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -2.0268 |
| RIC8B | RIC8 guanine nucleotide exchange factor B | -2.01825 |
| HSPA8 | heat shock 70kDa protein 8 | -2.01737 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -2.01605 |
| ND5 | NADH dehydrogenase subunit 5 | -2.01565 |
| LHX2 | LIM homeobox 2 | -2.0152 |
| DACH1 | dachshund family transcription factor 1 | -2.0111 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide | -2.0101 |
| PRAME | preferentially expressed antigen in melanoma | -2.00605 |
