CRCGN008_HEPG2_24H:N06 Gene Set
Genes
51 genes differentially expressed following the CRCGN008_HEPG2_24H:N06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
5.1144
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.10125
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.82735
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.6578
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.3802
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.5754
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.40377
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.2684
|
|
NMU
|
neuromedin U
|
3.24545
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.16243
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.99845
|
|
CCNA1
|
cyclin A1
|
2.9427
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.77225
|
|
CCNF
|
cyclin F
|
2.73898
|
|
HEBP1
|
heme binding protein 1
|
2.7129
|
|
GPATCH8
|
G patch domain containing 8
|
2.65557
|
|
CTSL
|
cathepsin L
|
2.5176
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.5096
|
|
GATA2
|
GATA binding protein 2
|
2.46742
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.3321
|
|
CYCS
|
cytochrome c, somatic
|
2.25615
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.22145
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.1341
|
|
MAPKAPK2
|
mitogen-activated protein kinase-activated protein kinase 2
|
2.04045
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.03813
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-7.52965
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-5.65295
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-5.43005
|
|
CCDC86
|
coiled-coil domain containing 86
|
-5.37735
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.0711
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.8024
|
|
NUP85
|
nucleoporin 85kDa
|
-4.6737
|
|
CCNB2
|
cyclin B2
|
-4.66275
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.6251
|
|
CD320
|
CD320 molecule
|
-4.46615
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.0442
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-3.02663
|
|
CD58
|
CD58 molecule
|
-2.88467
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.85515
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.6758
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-2.57125
|
|
WASHC4
|
WASH complex subunit 4
|
-2.45752
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.40355
|
|
CERS2
|
ceramide synthase 2
|
-2.29885
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.18047
|
|
FAM174B
|
family with sequence similarity 174, member B
|
-2.14313
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.12235
|
|
YPEL1
|
yippee-like 1 (Drosophila)
|
-2.07285
|
|
CNNM3
|
cyclin and CBS domain divalent metal cation transport mediator 3
|
-2.07055
|
|
PDIA5
|
protein disulfide isomerase family A, member 5
|
-2.0468
|
|
NVL
|
nuclear VCP-like
|
-2.03115
|
