| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | pyrazinamide 19.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN008_HEPG2_24H:N08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHN1 | chimerin 1 | 6.89485 |
| HEBP1 | heme binding protein 1 | 5.20605 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.11935 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.1128 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 4.89735 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.6568 |
| PRR15L | proline rich 15-like | 4.33765 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.96945 |
| STXBP2 | syntaxin binding protein 2 | 3.8374 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.787 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.60254 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.5321 |
| TBP | TATA box binding protein | 3.36005 |
| GATA3 | GATA binding protein 3 | 3.27185 |
| SFTPB | surfactant protein B | 3.14102 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.10217 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 2.41008 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.3882 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.35832 |
| ADIPOR1 | adiponectin receptor 1 | 2.29815 |
| ARHGAP17 | Rho GTPase activating protein 17 | 2.2352 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.21385 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) | 2.19795 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.17665 |
| MTA2 | metastasis associated 1 family, member 2 | 2.1592 |
| GET3 | guided entry of tail-anchored proteins factor 3, ATPase | 2.1542 |
| TXNL4B | thioredoxin-like 4B | 2.1515 |
| SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 2.13226 |
| SNF8 | SNF8, ESCRT-II complex subunit | 2.04935 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 | 2.03935 |
| THOC6 | THO complex 6 | 2.0296 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -5.61735 |
| TLCD3A | TLC domain containing 3A | -5.42035 |
| GOLT1B | golgi transport 1B | -4.69505 |
| LDHD | lactate dehydrogenase D | -4.66275 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.5619 |
| MTA1 | metastasis associated 1 | -3.39523 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.33915 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -3.2919 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -3.01787 |
| TOMM70 | translocase of outer mitochondrial membrane 70 | -2.9606 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.88345 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.75335 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.5774 |
| NLRP4 | NLR family, pyrin domain containing 4 | -2.51465 |
| GOLGB1 | golgin B1 | -2.45603 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -2.33698 |
| TSPYL5 | TSPY-like 5 | -2.14025 |
| CCNB1 | cyclin B1 | -2.11285 |
| DENND4C | DENN/MADD domain containing 4C | -2.10935 |
| YAF2 | YY1 associated factor 2 | -2.0971 |
| TJP2 | tight junction protein 2 | -2.0836 |
| SLC35F2 | solute carrier family 35, member F2 | -2.0733 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -2.06565 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -2.03285 |
| BMP4 | bone morphogenetic protein 4 | -2.031 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | -2.0247 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.0049 |
