| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | pyrazinamide 2.47 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
66 genes differentially expressed following the CRCGN008_HEPG2_24H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.5762 |
| CCNF | cyclin F | 5.3325 |
| RPL39L | ribosomal protein L39-like | 5.28735 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.0798 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.07415 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.0 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.7291 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.6957 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.4485 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.40785 |
| ABHD6 | abhydrolase domain containing 6 | 3.96435 |
| MAP7 | microtubule-associated protein 7 | 3.41912 |
| CYCS | cytochrome c, somatic | 3.3794 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 3.14805 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.87075 |
| WDR7 | WD repeat domain 7 | 2.727 |
| CHN1 | chimerin 1 | 2.71025 |
| CDCA3 | cell division cycle associated 3 | 2.68065 |
| SLC75A1 | solute carrier family 75 member 1 | 2.67195 |
| NOP2 | NOP2 nucleolar protein | 2.5874 |
| KIF20A | kinesin family member 20A | 2.5679 |
| JADE2 | jade family PHD finger 2 | 2.54212 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.3772 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 2.3733 |
| FADD | Fas (TNFRSF6)-associated via death domain | 2.3321 |
| RPA3 | replication protein A3, 14kDa | 2.31125 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.24745 |
| OLFML2B | olfactomedin-like 2B | 2.24565 |
| WASF3 | WAS protein family, member 3 | 2.1942 |
| DOLK | dolichol kinase | 2.184 |
| OSBPL1A | oxysterol binding protein-like 1A | 2.11645 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 2.1013 |
| IP6K2 | inositol hexakisphosphate kinase 2 | 2.07 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | 2.00085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.36995 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.16675 |
| TUBB6 | tubulin, beta 6 class V | -5.11075 |
| VAT1 | vesicle amine transport 1 | -5.0165 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.95355 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -4.7531 |
| LDHD | lactate dehydrogenase D | -4.479 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.89708 |
| GNAS | GNAS complex locus | -3.74445 |
| CCNB2 | cyclin B2 | -3.1212 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.7021 |
| PLA2G15 | phospholipase A2, group XV | -2.66475 |
| ELAC2 | elaC ribonuclease Z 2 | -2.5272 |
| STAMBP | STAM binding protein | -2.45305 |
| CD4 | CD4 molecule | -2.44115 |
| CAPN10 | calpain 10 | -2.35015 |
| CSRP1 | cysteine and glycine-rich protein 1 | -2.33123 |
| HSPA8 | heat shock 70kDa protein 8 | -2.28958 |
| EIF1 | eukaryotic translation initiation factor 1 | -2.24226 |
| GPATCH2L | G patch domain containing 2-like | -2.23105 |
| TAGLN3 | transgelin 3 | -2.2117 |
| TRIM49D2 | tripartite motif containing 49D2 | -2.18985 |
| ZW10 | zw10 kinetochore protein | -2.18085 |
| KCTD20 | potassium channel tetramerization domain containing 20 | -2.1736 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -2.14265 |
| RAB1B | RAB1B, member RAS oncogene family | -2.1091 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.0969 |
| CORO2B | coronin, actin binding protein, 2B | -2.0886 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -2.0792 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.0682 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -2.06125 |
| DEK | DEK proto-oncogene | -2.00425 |
