| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | fluconazole 10.45 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN008_HEPG2_24H:N14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAGE3 | L antigen family, member 3 | 5.79675 |
| GPATCH8 | G patch domain containing 8 | 5.66843 |
| MYLK | myosin light chain kinase | 5.32895 |
| STIMATE | STIM activating enhancer | 5.2857 |
| KLHL21 | kelch-like family member 21 | 5.1665 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 4.99065 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.86945 |
| ADRB2 | adrenoceptor beta 2, surface | 4.7629 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4.73952 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.31605 |
| PRKCH | protein kinase C, eta | 4.0268 |
| PRR15L | proline rich 15-like | 3.6811 |
| EVL | Enah/Vasp-like | 3.6136 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.53 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.08433 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.013 |
| DENND2D | DENN/MADD domain containing 2D | 2.94835 |
| MAP7 | microtubule-associated protein 7 | 2.9265 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.77245 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.59238 |
| USP6NL | USP6 N-terminal like | 2.56055 |
| SSR4 | signal sequence receptor, delta | 2.5123 |
| POLK | polymerase (DNA directed) kappa | 2.38005 |
| TAC4 | tachykinin 4 (hemokinin) | 2.3445 |
| RETREG3 | reticulophagy regulator family member 3 | 2.29755 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.25898 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 2.22695 |
| GPC3 | glypican 3 | 2.17335 |
| NOSIP | nitric oxide synthase interacting protein | 2.1186 |
| VEGFD | vascular endothelial growth factor D | 2.0598 |
| AOC3 | amine oxidase, copper containing 3 | 2.05295 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.02305 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 2.02185 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 2.006 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.00353 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC20 | cell division cycle 20 | -5.62735 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.36215 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.25125 |
| CD320 | CD320 molecule | -5.09075 |
| ZNF586 | zinc finger protein 586 | -5.08995 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -5.0 |
| INPP1 | inositol polyphosphate-1-phosphatase | -4.8296 |
| TLCD3A | TLC domain containing 3A | -4.66935 |
| LDHD | lactate dehydrogenase D | -4.5593 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.52435 |
| PCNA | proliferating cell nuclear antigen | -4.2674 |
| SLC35F2 | solute carrier family 35, member F2 | -4.26425 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -4.0021 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.77717 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.5007 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.22275 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.1741 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.9432 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.74525 |
| SNX11 | sorting nexin 11 | -2.6125 |
| PEG10 | paternally expressed 10 | -2.5 |
| GOLM1 | golgi membrane protein 1 | -2.27815 |
| OXCT1 | 3-oxoacid CoA transferase 1 | -2.2546 |
| COQ4 | coenzyme Q4 | -2.1932 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -2.182 |
| STAB1 | stabilin 1 | -2.17663 |
| NLGN1 | neuroligin 1 | -2.13945 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.12663 |
| ADGRG3 | adhesion G protein-coupled receptor G3 | -2.0941 |
| ANAPC2 | anaphase promoting complex subunit 2 | -2.07905 |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) | -2.03665 |
| RTN3 | reticulon 3 | -2.0212 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -2.01735 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | -2.014 |
