| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | fluconazole 1.31 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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57 genes differentially expressed following the CRCGN008_HEPG2_24H:N17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 10.0 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 6.9579 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.2311 |
| E2F2 | E2F transcription factor 2 | 5.11755 |
| MYLK | myosin light chain kinase | 5.1068 |
| RPL39L | ribosomal protein L39-like | 4.97705 |
| SMIM40 | small integral membrane protein 40 | 4.8763 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.79755 |
| CBR3 | carbonyl reductase 3 | 4.68005 |
| CEP57 | centrosomal protein 57kDa | 4.38742 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 4.29752 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.09525 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.651 |
| NMU | neuromedin U | 3.59445 |
| LOC122526780 | uncharacterized LOC122526780 | 3.57045 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.56 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 3.0601 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.9663 |
| SATB1 | SATB homeobox 1 | 2.8561 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.77513 |
| TBP | TATA box binding protein | 2.7126 |
| JADE2 | jade family PHD finger 2 | 2.62348 |
| DALRD3 | DALR anticodon binding domain containing 3 | 2.18975 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 2.1502 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.10229 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.0978 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 | 2.0924 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 2.05 |
| MAGEA4 | melanoma antigen family A4 | 2.0414 |
| CBX7 | chromobox homolog 7 | 2.03965 |
| S100A7 | S100 calcium binding protein A7 | 2.0299 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.63265 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.51975 |
| CD320 | CD320 molecule | -5.1748 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| TRIB3 | tribbles pseudokinase 3 | -4.94 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.8634 |
| DNM1L | dynamin 1-like | -4.85635 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.72195 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.3238 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.2502 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.9339 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -3.46208 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.1631 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.01427 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.6834 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.54685 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.4638 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 | -2.33165 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.29575 |
| NGRN | neugrin, neurite outgrowth associated | -2.23205 |
| CCNB1 | cyclin B1 | -2.19095 |
| ZFHX3 | zinc finger homeobox 3 | -2.1694 |
| TXNRD1 | thioredoxin reductase 1 | -2.1463 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.1254 |
| ZC3H7A | zinc finger CCCH-type containing 7A | -2.03625 |
| MAOA | monoamine oxidase A | -2.00438 |
