| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | beta-carotene 10.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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76 genes differentially expressed following the CRCGN008_HEPG2_24H:O08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.0999 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.07915 |
| EAPP | E2F-associated phosphoprotein | 4.9654 |
| LSR | lipolysis stimulated lipoprotein receptor | 4.8068 |
| STK10 | serine/threonine kinase 10 | 4.73465 |
| UBQLN2 | ubiquilin 2 | 4.63275 |
| RPL39L | ribosomal protein L39-like | 4.59295 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.56415 |
| ADRB2 | adrenoceptor beta 2, surface | 4.5355 |
| NOTCH1 | notch 1 | 4.53395 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.42105 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.30598 |
| EGF | epidermal growth factor | 4.30365 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.0571 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.96465 |
| CHN1 | chimerin 1 | 3.8999 |
| MAMLD1 | mastermind-like domain containing 1 | 3.79705 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.62445 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.52815 |
| ABHD4 | abhydrolase domain containing 4 | 3.48085 |
| HEBP1 | heme binding protein 1 | 3.3606 |
| STXBP2 | syntaxin binding protein 2 | 3.2848 |
| CCDC85B | coiled-coil domain containing 85B | 3.03695 |
| CCNF | cyclin F | 2.95103 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.86945 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 2.7529 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.64892 |
| LOC122526780 | uncharacterized LOC122526780 | 2.639 |
| CYCS | cytochrome c, somatic | 2.48565 |
| KLHL9 | kelch-like family member 9 | 2.4807 |
| LPL | lipoprotein lipase | 2.32888 |
| SRPX | sushi-repeat containing protein, X-linked | 2.31725 |
| CEP57 | centrosomal protein 57kDa | 2.19302 |
| SLC6A1 | solute carrier family 6 (neurotransmitter transporter), member 1 | 2.1888 |
| RAB4A | RAB4A, member RAS oncogene family | 2.05298 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.03848 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.45675 |
| CHMP4B | charged multivesicular body protein 4B | -5.20003 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -5.16135 |
| TRIB3 | tribbles pseudokinase 3 | -5.0804 |
| RAI14 | retinoic acid induced 14 | -4.9769 |
| TLCD3A | TLC domain containing 3A | -4.85735 |
| CD320 | CD320 molecule | -4.66275 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.54915 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.1935 |
| TES | testin LIM domain protein | -3.80395 |
| ANKRD10 | ankyrin repeat domain 10 | -3.4407 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -3.4117 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -3.0851 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.0069 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -2.83707 |
| SLC35F2 | solute carrier family 35, member F2 | -2.75875 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.63775 |
| COXFA4L2 | cytochrome c oxidase hypoxia associated subunit FA4L2 | -2.51575 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.47892 |
| SLC22A17 | solute carrier family 22, member 17 | -2.4249 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) | -2.4055 |
| VEGFA | vascular endothelial growth factor A | -2.36594 |
| SIRT6 | sirtuin 6 | -2.30295 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 | -2.28485 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.2674 |
| RBM34 | RNA binding motif protein 34 | -2.23752 |
| PKD2L1 | polycystic kidney disease 2-like 1 | -2.22715 |
| MAGED4B | melanoma antigen family D4B | -2.22545 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 | -2.1958 |
| PCDH17 | protocadherin 17 | -2.18735 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.13367 |
| SNRNP27 | small nuclear ribonucleoprotein 27kDa (U4/U6.U5) | -2.07708 |
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | -2.0645 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 | -2.0634 |
| SHISAL1 | shisa like 1 | -2.0621 |
| S100A3 | S100 calcium binding protein A3 | -2.0457 |
| FAM117A | family with sequence similarity 117, member A | -2.0422 |
| CIDEB | cell death-inducing DFFA-like effector b | -2.03095 |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) | -2.01005 |
| FHL2 | four and a half LIM domains 2 | -2.0063 |
