| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | beta-carotene 5.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN008_HEPG2_24H:O09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.74295 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.36345 |
| RAB21 | RAB21, member RAS oncogene family | 5.3276 |
| STK10 | serine/threonine kinase 10 | 5.28685 |
| ADRB2 | adrenoceptor beta 2, surface | 5.1385 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.08485 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.94405 |
| CYCS | cytochrome c, somatic | 4.91 |
| LSR | lipolysis stimulated lipoprotein receptor | 4.86745 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 4.3781 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 4.2347 |
| CHN1 | chimerin 1 | 4.1142 |
| ARL4C | ADP-ribosylation factor-like 4C | 3.93312 |
| PRR15L | proline rich 15-like | 3.84895 |
| ZNF589 | zinc finger protein 589 | 3.76378 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 3.45503 |
| MOK | MOK protein kinase | 3.34145 |
| ABHD4 | abhydrolase domain containing 4 | 2.925 |
| TENT2 | terminal nucleotidyltransferase 2 | 2.8306 |
| JADE2 | jade family PHD finger 2 | 2.825 |
| HEBP1 | heme binding protein 1 | 2.78945 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.7767 |
| MAMLD1 | mastermind-like domain containing 1 | 2.72835 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.6674 |
| CCNF | cyclin F | 2.63415 |
| STXBP1 | syntaxin binding protein 1 | 2.43925 |
| HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | 2.3629 |
| FKTN | fukutin | 2.359 |
| EPHA3 | EPH receptor A3 | 2.31288 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.24182 |
| EBLN2 | endogenous Bornavirus-like nucleoprotein 2 | 2.2305 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.17653 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 2.12847 |
| SLC2A4RG | SLC2A4 regulator | 2.0996 |
| SACM1L | SAC1 suppressor of actin mutations 1-like (yeast) | 2.08135 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.07482 |
| KLHL9 | kelch-like family member 9 | 2.07025 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.06238 |
| VGLL4 | vestigial-like family member 4 | 2.04405 |
| CDCA4 | cell division cycle associated 4 | 2.0212 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -8.05555 |
| FAIM | Fas apoptotic inhibitory molecule | -5.56855 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.04105 |
| LDHD | lactate dehydrogenase D | -4.87525 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.85895 |
| ADI1 | acireductone dioxygenase 1 | -4.7295 |
| CCNB2 | cyclin B2 | -4.70205 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -4.197 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.9834 |
| PCNA | proliferating cell nuclear antigen | -3.92795 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -3.67457 |
| GDF15 | growth differentiation factor 15 | -3.6011 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.58265 |
| GALE | UDP-galactose-4-epimerase | -3.4545 |
| CAB39 | calcium binding protein 39 | -3.43105 |
| COG2 | component of oligomeric golgi complex 2 | -3.42675 |
| WASHC4 | WASH complex subunit 4 | -3.27283 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.08645 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.99798 |
| RNF167 | ring finger protein 167 | -2.9101 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.6065 |
| SKIC2 | SKI2 subunit of superkiller complex | -2.4115 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.33905 |
| IRF1 | interferon regulatory factor 1 | -2.32475 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.2111 |
| BDKRB2 | bradykinin receptor B2 | -2.1962 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -2.1861 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -2.1664 |
| SMC3 | structural maintenance of chromosomes 3 | -2.05688 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.0258 |
