| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | beta-carotene 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN008_HEPG2_24H:O11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.92995 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.92485 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.9144 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.89435 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.8761 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.33565 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.33243 |
| PRR15L | proline rich 15-like | 4.29465 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.88245 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.7188 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.65195 |
| VGLL4 | vestigial-like family member 4 | 3.48238 |
| CCDC85B | coiled-coil domain containing 85B | 3.44705 |
| CHMP6 | charged multivesicular body protein 6 | 3.15345 |
| MAP7 | microtubule-associated protein 7 | 3.08552 |
| H2BC12 | H2B clustered histone 12 | 2.89577 |
| LOC122526780 | uncharacterized LOC122526780 | 2.87555 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.82402 |
| CCNF | cyclin F | 2.71722 |
| LSR | lipolysis stimulated lipoprotein receptor | 2.40105 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.39988 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.3048 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.19412 |
| SCHIP1 | schwannomin interacting protein 1 | 2.1729 |
| TLR4 | toll-like receptor 4 | 2.10085 |
| GPATCH8 | G patch domain containing 8 | 2.08253 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 2.07395 |
| AXIN1 | axin 1 | 2.06675 |
| DNAAF11 | dynein axonemal assembly factor 11 | 2.04925 |
| SIK2 | salt-inducible kinase 2 | 2.0324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLCD3A | TLC domain containing 3A | -8.67465 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.1595 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -5.0582 |
| VAT1 | vesicle amine transport 1 | -4.838 |
| TSPAN4 | tetraspanin 4 | -4.74955 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.38255 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.27845 |
| CCNB2 | cyclin B2 | -3.9605 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.55717 |
| CSNK1E | casein kinase 1, epsilon | -3.41687 |
| TOR1A | torsin family 1, member A (torsin A) | -3.41223 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.99084 |
| ANKRD10 | ankyrin repeat domain 10 | -2.81905 |
| CLTB | clathrin, light chain B | -2.75785 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.66778 |
| WASHC4 | WASH complex subunit 4 | -2.44905 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.40095 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.39262 |
| HSPA8 | heat shock 70kDa protein 8 | -2.28622 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.26815 |
| CHRDL1 | chordin-like 1 | -2.2134 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.2091 |
| PGM1 | phosphoglucomutase 1 | -2.08675 |
| LIN7B | lin-7 homolog B (C. elegans) | -2.083 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.0676 |
| RBM15B | RNA binding motif protein 15B | -2.0545 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -2.0533 |
| ZNF274 | zinc finger protein 274 | -2.03805 |
