CRCGN008_HEPG2_24H:O12 Gene Set
Genes
42 genes differentially expressed following the CRCGN008_HEPG2_24H:O12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
6.1812
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.1486
|
|
JADE2
|
jade family PHD finger 2
|
5.0534
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.0467
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.98065
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.82655
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.7875
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.54145
|
|
ZFP36
|
ZFP36 ring finger protein
|
3.7785
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.01275
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.9523
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.7547
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.69733
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.683
|
|
CYCS
|
cytochrome c, somatic
|
2.6266
|
|
FPGS
|
folylpolyglutamate synthase
|
2.49685
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.41625
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.33978
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.2703
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.26975
|
|
SFTPB
|
surfactant protein B
|
2.10253
|
|
LRRC8D
|
leucine rich repeat containing 8 family, member D
|
2.02855
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-5.22815
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.10685
|
|
CD320
|
CD320 molecule
|
-4.9929
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.95415
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.9349
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-4.85248
|
|
LDHD
|
lactate dehydrogenase D
|
-4.59515
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.5612
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-3.3246
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.11835
|
|
CLIC4
|
chloride intracellular channel 4
|
-3.00408
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.73352
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.59515
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.22808
|
|
H2BC6
|
H2B clustered histone 6
|
-2.18895
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
-2.07165
|
|
TLR1
|
toll-like receptor 1
|
-2.0672
|
|
PINK1
|
PTEN induced putative kinase 1
|
-2.05422
|
|
ANGPTL2
|
angiopoietin-like 2
|
-2.03798
|
|
H1-10
|
H1.10 linker histone
|
-2.02155
|
