CRCGN008_HEPG2_24H:O14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3'-methyl-4-dimethylaminoazobenzene 24.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

530 genes differentially expressed following the CRCGN008_HEPG2_24H:O14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
CBR3 carbonyl reductase 3 9.80545
TXNRD1 thioredoxin reductase 1 7.5676
TRIB3 tribbles pseudokinase 3 7.15905
ABHD4 abhydrolase domain containing 4 7.13865
INPP1 inositol polyphosphate-1-phosphatase 7.0587
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 6.91983
DDIT4 DNA-damage-inducible transcript 4 6.06105
KLHL21 kelch-like family member 21 5.98575
PRAF2 PRA1 domain family, member 2 5.96155
DDB2 damage-specific DNA binding protein 2, 48kDa 5.9367
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 5.9219
LCN2 lipocalin 2 5.88025
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.8345
ANKRD10 ankyrin repeat domain 10 5.76205
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 5.57805
FOSL1 FOS-like antigen 1 5.5338
KHDC4 KH domain containing 4, pre-mRNA splicing factor 5.51985
KEAP1 kelch-like ECH-associated protein 1 5.4737
ADRB2 adrenoceptor beta 2, surface 5.24045
BLCAP bladder cancer associated protein 5.1714
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 5.1025
TUBB6 tubulin, beta 6 class V 4.88725
CCP110 centriolar coiled coil protein 110kDa 4.8208
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 4.7594
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 4.7329
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 4.7126
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4.6771
RRAGA Ras-related GTP binding A 4.66195
ZBTB35 zinc finger and BTB domain containing 35 4.60468
RALGDS ral guanine nucleotide dissociation stimulator 4.58673
LOC122526780 uncharacterized LOC122526780 4.56045
STX1A syntaxin 1A (brain) 4.4783
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.3431
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.33315
TBC1D31 TBC1 domain family, member 31 4.2833
NISCH nischarin 4.1347
MICALL1 MICAL-like 1 4.12795
RGS2 regulator of G-protein signaling 2 4.05915
SQSTM1 sequestosome 1 4.0334
SESN1 sestrin 1 3.9856
VAT1 vesicle amine transport 1 3.9356
RAP1GAP RAP1 GTPase activating protein 3.75325
DUSP14 dual specificity phosphatase 14 3.73705
IL4R interleukin 4 receptor 3.613
GPATCH8 G patch domain containing 8 3.50082
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.475
IER3 immediate early response 3 3.4107
VAV3 vav 3 guanine nucleotide exchange factor 3.4066
MYLK myosin light chain kinase 3.355
GADD45A growth arrest and DNA-damage-inducible, alpha 3.3108
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 3.30015
FNBP4 formin binding protein 4 3.2885
SCYL3 SCY1-like 3 (S. cerevisiae) 3.25338
PRKCH protein kinase C, eta 3.15978
TBC1D3G TBC1 domain family member 3G 3.15115
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 3.12995
NANOS3 nanos homolog 3 (Drosophila) 3.1138
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.1066
IGHMBP2 immunoglobulin mu binding protein 2 3.08307
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.0784
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.05815
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.00423
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 3.0001
SKIC2 SKI2 subunit of superkiller complex 2.9834
TERT telomerase reverse transcriptase 2.979
TCERG1 transcription elongation regulator 1 2.9726
TERF2IP telomeric repeat binding factor 2, interacting protein 2.95925
ELAC2 elaC ribonuclease Z 2 2.9288
PLK3 polo-like kinase 3 2.9164
KDM5A lysine (K)-specific demethylase 5A 2.91278
AEN apoptosis enhancing nuclease 2.89285
TUT7 terminal uridylyl transferase 7 2.88065
PRR15L proline rich 15-like 2.84685
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.8291
NRDC nardilysin convertase 2.8197
TRIM66 tripartite motif containing 66 2.813
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.8015
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.7721
PRKCD protein kinase C, delta 2.76605
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.76035
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.74825
DNM1L dynamin 1-like 2.74005
GPC1 glypican 1 2.73257
DUSP6 dual specificity phosphatase 6 2.7208
NPIPB5 nuclear pore complex interacting protein family, member B5 2.71905
PILRB paired immunoglobin-like type 2 receptor beta 2.7115
CDC25B cell division cycle 25B 2.70825
CDCA4 cell division cycle associated 4 2.7057
CAMTA2 calmodulin binding transcription activator 2 2.6767
TOMM34 translocase of outer mitochondrial membrane 34 2.6723
CYCS cytochrome c, somatic 2.66245
PHGDH phosphoglycerate dehydrogenase 2.6483
ULK1 unc-51 like autophagy activating kinase 1 2.6437
TRIP12 thyroid hormone receptor interactor 12 2.63755
MCOLN1 mucolipin 1 2.6315
TTC19 tetratricopeptide repeat domain 19 2.62795
SAMD9 sterile alpha motif domain containing 9 2.6048
NOLC1 nucleolar and coiled-body phosphoprotein 1 2.58898
PNKP polynucleotide kinase 3'-phosphatase 2.5719
CNPY3 canopy FGF signaling regulator 3 2.5436
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.54277
TEX10 testis expressed 10 2.54145
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.52338
ZCCHC8 zinc finger, CCHC domain containing 8 2.5226
ODR4 odr-4 GPCR localization factor homolog 2.519
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.51735
PLD2 phospholipase D2 2.51655
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 2.51115
XPC xeroderma pigmentosum, complementation group C 2.5083
ABHD6 abhydrolase domain containing 6 2.50738
PTPN9 protein tyrosine phosphatase, non-receptor type 9 2.5059
FDXR ferredoxin reductase 2.48975
KDM6B lysine (K)-specific demethylase 6B 2.47638
MUTYH mutY homolog 2.46725
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.4582
COQ4 coenzyme Q4 2.4568
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 2.45675
PSPC1 paraspeckle component 1 2.45465
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.4544
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.4491
ZFPM1 zinc finger protein, FOG family member 1 2.4439
DVL3 dishevelled segment polarity protein 3 2.4374
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.4363
S100PBP S100P binding protein 2.433
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.43225
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.41885
LARP6 La ribonucleoprotein domain family, member 6 2.41815
TJAP1 tight junction associated protein 1 (peripheral) 2.41515
ELMO3 engulfment and cell motility 3 2.40945
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.4039
CCNL2 cyclin L2 2.39845
ZDHHC11B zinc finger, DHHC-type containing 11B 2.3921
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.39125
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 2.39108
COL7A1 collagen, type VII, alpha 1 2.38998
ECD ecdysoneless homolog (Drosophila) 2.3866
HPSE heparanase 2.38025
SACS sacsin molecular chaperone 2.37985
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.37295
CALCOCO2 calcium binding and coiled-coil domain 2 2.36915
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.3686
APOL6 apolipoprotein L, 6 2.36465
KDM5C lysine (K)-specific demethylase 5C 2.3522
NT5C2 5'-nucleotidase, cytosolic II 2.34045
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.3348
CDC45 cell division cycle 45 2.3318
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 2.3197
ADM adrenomedullin 2.2973
LSR lipolysis stimulated lipoprotein receptor 2.2964
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.29537
AARS1 alanyl-tRNA synthetase 1 2.29025
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.287
MYL5 myosin, light chain 5, regulatory 2.27955
TSC22D3 TSC22 domain family, member 3 2.2772
FOXK2 forkhead box K2 2.26515
CSRNP2 cysteine-serine-rich nuclear protein 2 2.26475
EIF6 eukaryotic translation initiation factor 6 2.2611
FAM193A family with sequence similarity 193, member A 2.26015
PHF2 PHD finger protein 2 2.25945
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.2534
UPP1 uridine phosphorylase 1 2.2413
ADPGK ADP-dependent glucokinase 2.23735
BTNL8 butyrophilin-like 8 2.23155
JPT1 Jupiter microtubule associated homolog 1 2.22995
CCNL1 cyclin L1 2.22905
IP6K2 inositol hexakisphosphate kinase 2 2.2285
GSTZ1 glutathione S-transferase zeta 1 2.227
CCNF cyclin F 2.21528
CASC3 cancer susceptibility candidate 3 2.21395
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.21329
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.2116
NQO1 NAD(P)H dehydrogenase, quinone 1 2.20872
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.2033
TASL TLR adaptor interacting with endolysosomal SLC15A4 2.20085
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.19245
NUP58 nucleoporin 58 2.191
TBPL1 TBP-like 1 2.18975
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 2.18145
TLR4 toll-like receptor 4 2.1655
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.1593
BBC3 BCL2 binding component 3 2.15715
RHOB ras homolog family member B 2.14795
UIMC1 ubiquitin interaction motif containing 1 2.14725
GABARAPL1 GABA(A) receptor-associated protein like 1 2.14708
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.14412
TKTL1 transketolase-like 1 2.13517
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.13345
ZFC3H1 zinc finger, C3H1-type containing 2.1325
ZNF282 zinc finger protein 282 2.1317
NBPF10 neuroblastoma breakpoint family, member 10 2.1222
RIN1 Ras and Rab interactor 1 2.12075
GRB10 growth factor receptor-bound protein 10 2.11992
ALAS1 5'-aminolevulinate synthase 1 2.11685
MAPK12 mitogen-activated protein kinase 12 2.11465
RXYLT1 ribitol xylosyltransferase 1 2.1131
DUSP5 dual specificity phosphatase 5 2.1103
EI24 etoposide induced 2.4 2.11025
LOC128125814 uncharacterized LOC128125814 2.10955
BTK Bruton agammaglobulinemia tyrosine kinase 2.10695
DUOX1 dual oxidase 1 2.10597
CD247 CD247 molecule 2.1037
ATRIP ATR interacting protein 2.0984
CST7 cystatin F (leukocystatin) 2.09825
TEX264 testis expressed 264 2.0966
ZNF557 zinc finger protein 557 2.09545
MTO1 mitochondrial tRNA translation optimization 1 2.0953
NUP85 nucleoporin 85kDa 2.09315
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 2.09135
EGR1 early growth response 1 2.07892
PRPF3 pre-mRNA processing factor 3 2.076
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.0695
KCTD9 potassium channel tetramerization domain containing 9 2.06835
TATDN2 TatD DNase domain containing 2 2.0625
KYNU kynureninase 2.06156
CDC37L1 cell division cycle 37-like 1 2.0587
CAPN1 calpain 1, (mu/I) large subunit 2.05685
TRAFD1 TRAF-type zinc finger domain containing 1 2.0566
ZNF79 zinc finger protein 79 2.04895
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 2.04725
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.0413
TBC1D2 TBC1 domain family, member 2 2.0403
CLIP1 CAP-GLY domain containing linker protein 1 2.03852
PARP6 poly (ADP-ribose) polymerase family, member 6 2.0351
TIGAR TP53 induced glycolysis regulatory phosphatase 2.0312
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.03062
H2AC25 H2A clustered histone 25 2.0253
BAK1 BCL2-antagonist/killer 1 2.0228
PSMC3IP PSMC3 interacting protein 2.01842
HROB homologous recombination factor with OB-fold 2.0178
TBC1D10B TBC1 domain family, member 10B 2.01495
SPACA9 sperm acrosome associated 9 2.0059
NPIPB4 nuclear pore complex interacting protein family, member B4 2.00367
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.0018
IRAK3 interleukin-1 receptor-associated kinase 3 2.00143

decreased expression

Symbol Name Standardized Value
GNAS GNAS complex locus -7.86174
MNAT1 MNAT CDK-activating kinase assembly factor 1 -7.331
B4GAT1 beta-1,4-glucuronyltransferase 1 -6.9774
PSRC1 proline/serine-rich coiled-coil 1 -6.84295
RPIA ribose 5-phosphate isomerase A -6.7874
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -6.78535
PECR peroxisomal trans-2-enoyl-CoA reductase -6.59345
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -6.53445
USP6NL USP6 N-terminal like -6.42195
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -5.97745
CCNB1 cyclin B1 -5.9217
PEG10 paternally expressed 10 -5.34905
ZMIZ1 zinc finger, MIZ-type containing 1 -5.34405
CDC20 cell division cycle 20 -5.26915
LDHD lactate dehydrogenase D -5.21985
ITFG1 integrin alpha FG-GAP repeat containing 1 -5.16255
PLS1 plastin 1 -5.1549
PUF60 poly-U binding splicing factor 60KDa -5.0546
ANO10 anoctamin 10 -4.9952
MSRA methionine sulfoxide reductase A -4.94065
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.93112
PROS1 protein S (alpha) -4.8166
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.8018
PCCB propionyl CoA carboxylase, beta polypeptide -4.63545
PGM1 phosphoglucomutase 1 -4.5927
ZW10 zw10 kinetochore protein -4.53
HMGA2 high mobility group AT-hook 2 -4.478
YME1L1 YME1-like 1 ATPase -4.43933
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.30875
RSU1 Ras suppressor protein 1 -4.1537
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -4.11853
SLC35F2 solute carrier family 35, member F2 -4.093
TM9SF2 transmembrane 9 superfamily member 2 -4.00805
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.9732
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -3.7768
ALDOC aldolase C, fructose-bisphosphate -3.7742
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.76978
DENND2D DENN/MADD domain containing 2D -3.76395
ECH1 enoyl CoA hydratase 1, peroxisomal -3.7586
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.7555
ADAM10 ADAM metallopeptidase domain 10 -3.71258
SCARB1 scavenger receptor class B, member 1 -3.70895
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.69328
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -3.5537
ISOC1 isochorismatase domain containing 1 -3.5509
PARP1 poly (ADP-ribose) polymerase 1 -3.51595
PRPF18 pre-mRNA processing factor 18 -3.506
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.46543
PGAM4 phosphoglycerate mutase family member 4 -3.39225
C2CD5 C2 calcium-dependent domain containing 5 -3.3784
SOAT2 sterol O-acyltransferase 2 -3.36652
DERA deoxyribose-phosphate aldolase (putative) -3.3264
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -3.30445
ICAM3 intercellular adhesion molecule 3 -3.24285
IDI1 isopentenyl-diphosphate delta isomerase 1 -3.13405
CD58 CD58 molecule -3.12012
ATP5F1C ATP synthase F1 subunit gamma -3.09207
AKAP8 A kinase (PRKA) anchor protein 8 -3.07457
SCGB1D1 secretoglobin, family 1D, member 1 -3.05813
PCP4 Purkinje cell protein 4 -3.0402
HYOU1 hypoxia up-regulated 1 -3.0283
NAV2 neuron navigator 2 -3.0124
KLHDC2 kelch domain containing 2 -2.9979
PRCP prolylcarboxypeptidase (angiotensinase C) -2.99155
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -2.96303
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.93984
CXCL2 chemokine (C-X-C motif) ligand 2 -2.9177
ENTREP2 endosomal transmembrane epsin interactor 2 -2.916
BTBD8 BTB (POZ) domain containing 8 -2.87435
PRUNE1 prune exopolyphosphatase 1 -2.86442
RPN2 ribophorin II -2.84308
GLYAT glycine-N-acyltransferase -2.83186
ILK integrin-linked kinase -2.8232
S100A4 S100 calcium binding protein A4 -2.819
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -2.81647
NLRP2B NLR family pyrin domain containing 2B -2.816
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -2.802
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.79307
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.78685
EDN1 endothelin 1 -2.78655
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) -2.7778
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -2.7661
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.74555
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.74265
RHOBTB1 Rho-related BTB domain containing 1 -2.73325
EMID1 EMI domain containing 1 -2.72435
CRELD2 cysteine-rich with EGF-like domains 2 -2.72325
PLK1 polo-like kinase 1 -2.7171
TLCD3A TLC domain containing 3A -2.71075
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -2.71073
PHKB phosphorylase kinase, beta -2.6586
MSX1 msh homeobox 1 -2.654
OXR1 oxidation resistance 1 -2.6397
CEP112 centrosomal protein 112kDa -2.6333
AICDA activation-induced cytidine deaminase -2.63175
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.61365
MOCS3 molybdenum cofactor synthesis 3 -2.60615
HAT1 histone acetyltransferase 1 -2.60575
STMN1 stathmin 1 -2.5971
LRRTM4 leucine rich repeat transmembrane neuronal 4 -2.5875
THNSL1 threonine synthase-like 1 (S. cerevisiae) -2.5819
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.56195
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.5449
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.54005
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -2.5314
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 -2.529
CFHR5 complement factor H-related 5 -2.5274
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -2.52615
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 -2.52385
CX3CL1 chemokine (C-X3-C motif) ligand 1 -2.52113
MATN2 matrilin 2 -2.5208
SLC66A2 solute carrier family 66 member 2 -2.5016
NLGN1 neuroligin 1 -2.49795
SCRIB scribbled planar cell polarity protein -2.4845
SOSTDC1 sclerostin domain containing 1 -2.48395
SORT1 sortilin 1 -2.48373
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.47675
NCAPD2 non-SMC condensin I complex, subunit D2 -2.4683
ZNF780A zinc finger protein 780A -2.4673
DCPS decapping enzyme, scavenger -2.4632
ATP5F1E ATP synthase F1 subunit epsilon -2.462
HDAC2 histone deacetylase 2 -2.4577
FIG4 FIG4 phosphoinositide 5-phosphatase -2.4537
TCTN1 tectonic family member 1 -2.44815
MDH1 malate dehydrogenase 1, NAD (soluble) -2.44745
CSRNP3 cysteine-serine-rich nuclear protein 3 -2.4338
IFNA2 interferon, alpha 2 -2.4332
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 -2.42545
ANO2 anoctamin 2, calcium activated chloride channel -2.4187
ZNF287 zinc finger protein 287 -2.41725
NRTN neurturin -2.41565
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -2.4153
TOP2A topoisomerase (DNA) II alpha 170kDa -2.41365
CDH18 cadherin 18, type 2 -2.4131
NLGN4Y neuroligin 4, Y-linked -2.412
TLL1 tolloid-like 1 -2.4107
PPP1R9A protein phosphatase 1, regulatory subunit 9A -2.41
DKK4 dickkopf WNT signaling pathway inhibitor 4 -2.40995
TUBA1C tubulin, alpha 1c -2.3999
NELFCD negative elongation factor complex member C/D -2.38765
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma -2.38085
KDM3A lysine (K)-specific demethylase 3A -2.3787
THEM6 thioesterase superfamily member 6 -2.37405
PDIA6 protein disulfide isomerase family A, member 6 -2.3667
ZNF250 zinc finger protein 250 -2.35615
NPTX1 neuronal pentraxin I -2.35115
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.3509
AURKB aurora kinase B -2.3476
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.34555
TMSB4X thymosin beta 4, X-linked -2.3429
EVL Enah/Vasp-like -2.3377
MTPAP mitochondrial poly(A) polymerase -2.33145
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.3314
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.3265
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -2.32498
PYCR3 pyrroline-5-carboxylate reductase 3 -2.31775
CNTN6 contactin 6 -2.3161
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.31235
JPH2 junctophilin 2 -2.30265
MARCKSL1 MARCKS-like 1 -2.3025
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.30043
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -2.2981
H3-3A H3.3 histone A -2.29631
TCEAL4 transcription elongation factor A (SII)-like 4 -2.2933
SPRYD7 SPRY domain containing 7 -2.29265
RIT2 Ras-like without CAAX 2 -2.2855
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 -2.28545
KIN Kin17 DNA and RNA binding protein -2.2834
KCTD11 potassium channel tetramerization domain containing 11 -2.27915
URI1 URI1, prefoldin-like chaperone -2.271
AKR1D1 aldo-keto reductase family 1, member D1 -2.2707
MINPP1 multiple inositol-polyphosphate phosphatase 1 -2.26545
PDE8B phosphodiesterase 8B -2.26355
CA10 carbonic anhydrase X -2.2581
NUCB2 nucleobindin 2 -2.2576
SNTG1 syntrophin, gamma 1 -2.25415
LDHA lactate dehydrogenase A -2.25255
COMMD10 COMM domain containing 10 -2.2524
FAM149A family with sequence similarity 149, member A -2.25153
MYLK3 myosin light chain kinase 3 -2.24995
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.24965
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -2.24485
PCDHB3 protocadherin beta 3 -2.24215
KIF14 kinesin family member 14 -2.23935
LPA lipoprotein, Lp(a) -2.23705
CHL1 cell adhesion molecule L1-like -2.2369
HNMT histamine N-methyltransferase -2.23653
OSBPL10 oxysterol binding protein-like 10 -2.23445
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.22905
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.2284
DNAAF2 dynein, axonemal, assembly factor 2 -2.2282
GPHN gephyrin -2.2244
LOC112694756 uncharaterized LOC112694756 -2.2241
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.21665
ZNF696 zinc finger protein 696 -2.2162
PPARA peroxisome proliferator-activated receptor alpha -2.2157
RNF103-CHMP3 RNF103-CHMP3 readthrough -2.2147
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -2.21355
E2F5 E2F transcription factor 5, p130-binding -2.2124
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -2.21192
FABP3 fatty acid binding protein 3, muscle and heart -2.20455
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.19765
AKT2 v-akt murine thymoma viral oncogene homolog 2 -2.19265
ITM2B integral membrane protein 2B -2.1838
FAM200C family with sequence similarity 200 member C -2.18265
INTS9 integrator complex subunit 9 -2.17795
CDK1 cyclin-dependent kinase 1 -2.1762
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.17605
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -2.175
PHF10 PHD finger protein 10 -2.1737
EML1 echinoderm microtubule associated protein like 1 -2.1732
ASXL3 additional sex combs like transcriptional regulator 3 -2.17305
UBE2N ubiquitin-conjugating enzyme E2N -2.17215
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -2.17058
LRP5 low density lipoprotein receptor-related protein 5 -2.1702
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.1692
HSF1 heat shock transcription factor 1 -2.16665
FXYD7 FXYD domain containing ion transport regulator 7 -2.1651
FGFR4 fibroblast growth factor receptor 4 -2.1635
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -2.16333
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -2.16115
SYT17 synaptotagmin XVII -2.16005
EPHA7 EPH receptor A7 -2.15565
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.15465
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.1544
FAT1 FAT atypical cadherin 1 -2.1543
KAT8 K(lysine) acetyltransferase 8 -2.15263
WDR7 WD repeat domain 7 -2.15025
ZBTB14 zinc finger and BTB domain containing 14 -2.1499
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.14937
ZNF274 zinc finger protein 274 -2.149
TMLHE trimethyllysine hydroxylase, epsilon -2.1448
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.14398
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.13805
MTARC1 mitochondrial amidoxime reducing component 1 -2.1346
EPHA5 EPH receptor A5 -2.1343
AANAT aralkylamine N-acetyltransferase -2.13115
MYL9 myosin, light chain 9, regulatory -2.12635
STMN3 stathmin-like 3 -2.12345
CUTA cutA divalent cation tolerance homolog (E. coli) -2.1228
PTK2B protein tyrosine kinase 2 beta -2.11868
PNPLA3 patatin-like phospholipase domain containing 3 -2.11775
ZXDB zinc finger, X-linked, duplicated B -2.1132
THAP9 THAP domain containing 9 -2.11285
MTNAP1 mitochondrial nucleoid associated protein 1 -2.108
SERF1A small EDRK-rich factor 1A (telomeric) -2.09755
FABP7 fatty acid binding protein 7, brain -2.09648
RPL36AL ribosomal protein L36a-like -2.0908
AGGF1 angiogenic factor with G patch and FHA domains 1 -2.08915
TBC1D22A TBC1 domain family, member 22A -2.08892
ZNF334 zinc finger protein 334 -2.0864
SGCE sarcoglycan, epsilon -2.0832
BLMH bleomycin hydrolase -2.07385
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.072
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.07005
SLC45A2 solute carrier family 45, member 2 -2.06995
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -2.0699
LRP6 low density lipoprotein receptor-related protein 6 -2.06205
TMEM50B transmembrane protein 50B -2.053
ATP5MG ATP synthase membrane subunit g -2.0518
PCBP1 poly(rC) binding protein 1 -2.0514
SHISAL1 shisa like 1 -2.0486
THAP11 THAP domain containing 11 -2.0477
LOC124907782 dual specificity protein phosphatase 22 -2.0474
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.04675
PLEKHA5 pleckstrin homology domain containing, family A member 5 -2.0462
ZNF16 zinc finger protein 16 -2.045
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -2.0447
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.04085
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 -2.03835
MOGS mannosyl-oligosaccharide glucosidase -2.03705
TRHDE thyrotropin-releasing hormone degrading enzyme -2.03265
FHL2 four and a half LIM domains 2 -2.031
GCM1 glial cells missing homolog 1 (Drosophila) -2.0304
ESM1 endothelial cell-specific molecule 1 -2.0266
IGF2 insulin-like growth factor 2 -2.02548
TUBA1B tubulin, alpha 1b -2.0252
ACTG1 actin gamma 1 -2.02376
LIPC lipase, hepatic -2.02375
SF3A1 splicing factor 3a, subunit 1, 120kDa -2.0163
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.0155
DIRAS2 DIRAS family, GTP-binding RAS-like 2 -2.01255
AGBL3 ATP/GTP binding protein-like 3 -2.01155
NDRG3 NDRG family member 3 -2.00953
LGALS8 lectin, galactoside-binding, soluble, 8 -2.0085
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -2.00683
WDR37 WD repeat domain 37 -2.00595
FGF3 fibroblast growth factor 3 -2.0056
RGN regucalcin -2.00475
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.0047
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 -2.00415
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -2.00385
ASB13 ankyrin repeat and SOCS box containing 13 -2.00385
CAPZB capping protein (actin filament) muscle Z-line, beta -2.00313
TLX2 T-cell leukemia homeobox 2 -2.00052