CRCGN008_HEPG2_24H:O24 Gene Set
Genes
45 genes differentially expressed following the CRCGN008_HEPG2_24H:O24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.71165
|
|
NOTCH1
|
notch 1
|
5.4596
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.9813
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.9517
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.94665
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.6676
|
|
MAP7
|
microtubule-associated protein 7
|
3.65348
|
|
PFKL
|
phosphofructokinase, liver
|
3.32477
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.15435
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
3.0462
|
|
USP6NL
|
USP6 N-terminal like
|
2.78185
|
|
CYCS
|
cytochrome c, somatic
|
2.672
|
|
IPO13
|
importin 13
|
2.66775
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.48555
|
|
NDRG1
|
N-myc downstream regulated 1
|
2.3721
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.34055
|
|
NFKBIE
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
|
2.26485
|
|
CSNK1A1
|
casein kinase 1, alpha 1
|
2.14351
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.1084
|
|
FAM53C
|
family with sequence similarity 53, member C
|
2.1069
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.08232
|
|
SELENOW
|
selenoprotein W
|
2.0623
|
|
TLR4
|
toll-like receptor 4
|
2.0358
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.6527
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-5.25915
|
|
CDC20
|
cell division cycle 20
|
-5.0
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.84395
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.7332
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.48195
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-4.2383
|
|
GNAS
|
GNAS complex locus
|
-4.18995
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-4.15845
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-3.77295
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.0727
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.68437
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.59608
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.5217
|
|
AURKB
|
aurora kinase B
|
-2.3661
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.3243
|
|
CD63
|
CD63 molecule
|
-2.31425
|
|
RIPPLY3
|
ripply transcriptional repressor 3
|
-2.19475
|
|
UBL3
|
ubiquitin-like 3
|
-2.1498
|
|
BACH2
|
BTB and CNC homology 1, basic leucine zipper transcription factor 2
|
-2.0984
|
|
CLEC2D
|
C-type lectin domain family 2, member D
|
-2.0635
|
|
CD5L
|
CD5 molecule-like
|
-2.0446
|
