| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tricresyl phosphate 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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116 genes differentially expressed following the CRCGN008_HEPG2_24H:P01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC45 | cell division cycle 45 | 6.8849 |
| CYCS | cytochrome c, somatic | 5.8655 |
| CBR3 | carbonyl reductase 3 | 5.7824 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.08495 |
| SATB1 | SATB homeobox 1 | 4.9969 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.8342 |
| ATP11B | ATPase, class VI, type 11B | 4.77945 |
| ADRB2 | adrenoceptor beta 2, surface | 4.74165 |
| USP6NL | USP6 N-terminal like | 4.12935 |
| UGDH | UDP-glucose 6-dehydrogenase | 3.9644 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.9346 |
| MELK | maternal embryonic leucine zipper kinase | 3.57325 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.32525 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 3.32075 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.11983 |
| MTERF3 | mitochondrial transcription termination factor 3 | 3.0157 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.8861 |
| KEAP1 | kelch-like ECH-associated protein 1 | 2.85355 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.8473 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 2.7686 |
| TXNRD1 | thioredoxin reductase 1 | 2.76575 |
| TWF2 | twinfilin actin binding protein 2 | 2.74045 |
| RAP1GAP | RAP1 GTPase activating protein | 2.6246 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 2.62125 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.6189 |
| CHN1 | chimerin 1 | 2.5972 |
| CRTAP | cartilage associated protein | 2.5732 |
| PMM2 | phosphomannomutase 2 | 2.5073 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.41735 |
| DDTL | D-dopachrome tautomerase-like | 2.35715 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 2.34645 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.3186 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.3178 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.31165 |
| PHGDH | phosphoglycerate dehydrogenase | 2.30573 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.2858 |
| NUCB2 | nucleobindin 2 | 2.249 |
| SLC46A3 | solute carrier family 46, member 3 | 2.24405 |
| STXBP2 | syntaxin binding protein 2 | 2.19105 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 2.1893 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.1889 |
| EML3 | echinoderm microtubule associated protein like 3 | 2.167 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 2.1471 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.11645 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.10195 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 | 2.09955 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 2.0984 |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 2.09675 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.0793 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | 2.07223 |
| ISG15 | ISG15 ubiquitin-like modifier | 2.07185 |
| FCHSD2 | FCH and double SH3 domains 2 | 2.04575 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 2.04505 |
| GCH1 | GTP cyclohydrolase 1 | 2.0262 |
| OSBPL3 | oxysterol binding protein-like 3 | 2.02428 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 2.00415 |
| FOXO4 | forkhead box O4 | 2.0011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.5585 |
| GOLT1B | golgi transport 1B | -5.8672 |
| CD320 | CD320 molecule | -5.13595 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.6707 |
| LDHD | lactate dehydrogenase D | -4.57485 |
| ZNF274 | zinc finger protein 274 | -4.53345 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.3148 |
| COG7 | component of oligomeric golgi complex 7 | -4.1395 |
| CDC20 | cell division cycle 20 | -4.07175 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.9673 |
| VAT1 | vesicle amine transport 1 | -3.93995 |
| RAI14 | retinoic acid induced 14 | -3.92015 |
| CDK1 | cyclin-dependent kinase 1 | -3.89892 |
| AURKB | aurora kinase B | -3.3973 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.3868 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.379 |
| NVL | nuclear VCP-like | -3.05795 |
| GPR63 | G protein-coupled receptor 63 | -3.03305 |
| PLK1 | polo-like kinase 1 | -3.0179 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.98975 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -2.9781 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.8508 |
| CCNB1 | cyclin B1 | -2.80765 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -2.79505 |
| CCN3 | cellular communication network factor 3 | -2.7083 |
| SNX11 | sorting nexin 11 | -2.64165 |
| CDC25B | cell division cycle 25B | -2.61725 |
| NGRN | neugrin, neurite outgrowth associated | -2.55425 |
| HAT1 | histone acetyltransferase 1 | -2.4988 |
| OPRK1 | opioid receptor, kappa 1 | -2.4668 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.40655 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -2.40545 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.39255 |
| HSPB1 | heat shock 27kDa protein 1 | -2.3876 |
| STMN1 | stathmin 1 | -2.3737 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.3652 |
| GRB7 | growth factor receptor-bound protein 7 | -2.33385 |
| CCNA2 | cyclin A2 | -2.32805 |
| ST7L | suppression of tumorigenicity 7 like | -2.29185 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -2.2627 |
| CCDC106 | coiled-coil domain containing 106 | -2.25 |
| PCDH8 | protocadherin 8 | -2.193 |
| ANGPT4 | angiopoietin 4 | -2.16405 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.15103 |
| PGAM4 | phosphoglycerate mutase family member 4 | -2.14895 |
| WNT6 | wingless-type MMTV integration site family, member 6 | -2.1452 |
| EPHA7 | EPH receptor A7 | -2.1235 |
| PARPBP | PARP1 binding protein | -2.11335 |
| SMIM40 | small integral membrane protein 40 | -2.09545 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 | -2.0789 |
| TSSC4 | tumor suppressing subtransferable candidate 4 | -2.06495 |
| BIRC5 | baculoviral IAP repeat containing 5 | -2.05793 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.05705 |
| NRCAM | neuronal cell adhesion molecule | -2.04662 |
| ANXA1 | annexin A1 | -2.03555 |
| SOCS2 | suppressor of cytokine signaling 2 | -2.02507 |
| SASH1 | SAM and SH3 domain containing 1 | -2.02095 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.00797 |
| IRS4 | insulin receptor substrate 4 | -2.0079 |
