| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tricresyl phosphate 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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78 genes differentially expressed following the CRCGN008_HEPG2_24H:P06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPATCH8 | G patch domain containing 8 | 5.16395 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.1025 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.0 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 4.57295 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.566 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.5572 |
| CBR3 | carbonyl reductase 3 | 4.54655 |
| ADRB2 | adrenoceptor beta 2, surface | 4.52025 |
| STAP2 | signal transducing adaptor family member 2 | 4.4638 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.2396 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.18695 |
| PRKCH | protein kinase C, eta | 3.85777 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.80008 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.0966 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.78868 |
| PIGG | phosphatidylinositol glycan anchor biosynthesis, class G | 2.55555 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.52725 |
| TBP | TATA box binding protein | 2.5265 |
| SLC75A1 | solute carrier family 75 member 1 | 2.49385 |
| PLSCR3 | phospholipid scramblase 3 | 2.46498 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.43573 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 2.33355 |
| USP6NL | USP6 N-terminal like | 2.29315 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 2.29295 |
| MYDGF | myeloid-derived growth factor | 2.23965 |
| DAZAP1 | DAZ associated protein 1 | 2.2306 |
| LOC122526780 | uncharacterized LOC122526780 | 2.1719 |
| CDC34 | cell division cycle 34 | 2.1586 |
| FAM8A1 | family with sequence similarity 8, member A1 | 2.12055 |
| SH3GL1 | SH3-domain GRB2-like 1 | 2.118 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.05535 |
| CDK7 | cyclin-dependent kinase 7 | 2.0401 |
| HEBP1 | heme binding protein 1 | 2.02445 |
| CCDC85C | coiled-coil domain containing 85C | 2.02425 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 2.00305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.94905 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.87155 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -4.79173 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.4778 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.14825 |
| RAI14 | retinoic acid induced 14 | -4.14685 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.8505 |
| GNAS | GNAS complex locus | -3.78964 |
| TXNRD1 | thioredoxin reductase 1 | -3.2452 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -3.20525 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.18485 |
| HSPA8 | heat shock 70kDa protein 8 | -3.07898 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.9237 |
| CCNB1 | cyclin B1 | -2.88325 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.8611 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.7729 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -2.73395 |
| FAIM | Fas apoptotic inhibitory molecule | -2.66035 |
| GALR1 | galanin receptor 1 | -2.5694 |
| HSPA1B | heat shock 70kDa protein 1B | -2.5664 |
| FRMPD4 | FERM and PDZ domain containing 4 | -2.526 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.5085 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.4733 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -2.37388 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -2.274 |
| PON3 | paraoxonase 3 | -2.26785 |
| TXNDC9 | thioredoxin domain containing 9 | -2.23548 |
| PRKCE | protein kinase C, epsilon | -2.1994 |
| SCN2A | sodium channel, voltage gated, type II alpha subunit | -2.1905 |
| RBM42 | RNA binding motif protein 42 | -2.18725 |
| PLPPR4 | phospholipid phosphatase related 4 | -2.16425 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 | -2.1293 |
| EGR4 | early growth response 4 | -2.1229 |
| CRHBP | corticotropin releasing hormone binding protein | -2.1127 |
| TPO | thyroid peroxidase | -2.1023 |
| RUNX2 | runt-related transcription factor 2 | -2.05657 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -2.05472 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -2.05135 |
| KLRC4-KLRK1 | KLRC4-KLRK1 readthrough | -2.03585 |
| USP27X | ubiquitin specific peptidase 27, X-linked | -2.01725 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | -2.0123 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -2.01105 |
