CRCGN008_HEPG2_24H:P08 Gene Set
Genes
41 genes differentially expressed following the CRCGN008_HEPG2_24H:P08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
6.26335
|
|
RPL39L
|
ribosomal protein L39-like
|
5.45865
|
|
E2F2
|
E2F transcription factor 2
|
5.4067
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.1578
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.80495
|
|
UBQLN2
|
ubiquilin 2
|
4.7608
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.5684
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.27165
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.02565
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.97528
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.7567
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.70295
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
3.53828
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
3.29973
|
|
CYCS
|
cytochrome c, somatic
|
3.26425
|
|
TBPL1
|
TBP-like 1
|
3.2053
|
|
PRR15L
|
proline rich 15-like
|
3.20465
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.08862
|
|
KIF5C
|
kinesin family member 5C
|
3.02285
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.90558
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.48183
|
|
EPHA3
|
EPH receptor A3
|
2.46828
|
|
USP6NL
|
USP6 N-terminal like
|
2.4608
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.3936
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.30995
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.29515
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.16835
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.6037
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.32735
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.87335
|
|
LDHD
|
lactate dehydrogenase D
|
-4.6982
|
|
VAT1
|
vesicle amine transport 1
|
-4.63645
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.56567
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
-2.6615
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.47575
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.36
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-2.1608
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.11508
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.08217
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.07085
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.03032
|
