| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | BRD-K63993117 5.08 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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73 genes differentially expressed following the CRCGN008_HEPG2_24H:P10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADRB2 | adrenoceptor beta 2, surface | 5.7572 |
| MOK | MOK protein kinase | 5.71865 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.5936 |
| MAMLD1 | mastermind-like domain containing 1 | 5.375 |
| CBR3 | carbonyl reductase 3 | 4.86845 |
| ATP11B | ATPase, class VI, type 11B | 4.31125 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.04558 |
| CHN1 | chimerin 1 | 4.0248 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.8831 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.7952 |
| EGF | epidermal growth factor | 3.70435 |
| PRR15L | proline rich 15-like | 3.5898 |
| ANO10 | anoctamin 10 | 3.53995 |
| PLSCR3 | phospholipid scramblase 3 | 3.38877 |
| CYCS | cytochrome c, somatic | 3.31295 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.79175 |
| CCNF | cyclin F | 2.73745 |
| KIF20A | kinesin family member 20A | 2.5874 |
| CCN6 | cellular communication network factor 6 | 2.555 |
| MAP7 | microtubule-associated protein 7 | 2.50192 |
| PMM2 | phosphomannomutase 2 | 2.49695 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.45113 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.4131 |
| WASF3 | WAS protein family, member 3 | 2.3821 |
| TBX2 | T-box 2 | 2.29187 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.23115 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.20925 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.18285 |
| SFTPB | surfactant protein B | 2.17645 |
| ANKRD28 | ankyrin repeat domain 28 | 2.14365 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 2.12365 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 2.07845 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 2.0201 |
| AMBP | alpha-1-microglobulin/bikunin precursor | 2.00695 |
| SMC5 | structural maintenance of chromosomes 5 | 2.00315 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.0015 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -6.8459 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.7344 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -6.1485 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.97985 |
| ZNF586 | zinc finger protein 586 | -4.83105 |
| TLCD3A | TLC domain containing 3A | -4.7563 |
| CCNB2 | cyclin B2 | -4.7503 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.681 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.12555 |
| GNAS | GNAS complex locus | -3.74059 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.4014 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.3225 |
| RBM42 | RNA binding motif protein 42 | -3.2504 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.00815 |
| PSENEN | presenilin enhancer gamma secretase subunit | -3.00385 |
| PDCD5 | programmed cell death 5 | -2.75895 |
| SNX11 | sorting nexin 11 | -2.67315 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.55465 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -2.53945 |
| ZYX | zyxin | -2.50517 |
| FCGBP | Fc fragment of IgG binding protein | -2.42175 |
| ZNF274 | zinc finger protein 274 | -2.3468 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.3435 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain | -2.29025 |
| ZFP36 | ZFP36 ring finger protein | -2.2156 |
| CDC25B | cell division cycle 25B | -2.2078 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -2.19278 |
| TACR2 | tachykinin receptor 2 | -2.1782 |
| NR2E1 | nuclear receptor subfamily 2, group E, member 1 | -2.1769 |
| TBCB | tubulin folding cofactor B | -2.1566 |
| NRN1 | neuritin 1 | -2.06955 |
| NDUFB4 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | -2.06185 |
| GFER | growth factor, augmenter of liver regeneration | -2.05675 |
| TRAPPC14 | trafficking protein particle complex subunit 14 | -2.0228 |
| STYXL1 | serine/threonine/tyrosine interacting-like 1 | -2.01365 |
| CAPNS1 | calpain, small subunit 1 | -2.00095 |
