CRCGN008_HEPG2_24H:P11 Gene Set
Genes
38 genes differentially expressed following the CRCGN008_HEPG2_24H:P11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
5.1626
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
5.13785
|
|
STK10
|
serine/threonine kinase 10
|
5.09575
|
|
NOTCH1
|
notch 1
|
4.97825
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.8361
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.79255
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.74607
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
4.0645
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.64145
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.25448
|
|
CHN1
|
chimerin 1
|
3.21335
|
|
MAP7
|
microtubule-associated protein 7
|
3.10258
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.59903
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.58828
|
|
USP6NL
|
USP6 N-terminal like
|
2.54695
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.27225
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.19833
|
|
EVL
|
Enah/Vasp-like
|
2.12925
|
|
CDCA4
|
cell division cycle associated 4
|
2.1125
|
|
STXBP2
|
syntaxin binding protein 2
|
2.04185
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.0114
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-5.0
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.80225
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.66275
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.60205
|
|
RPS5
|
ribosomal protein S5
|
-4.3845
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.56425
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.5241
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.2856
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.6902
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.48215
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.45435
|
|
RBM34
|
RNA binding motif protein 34
|
-2.40202
|
|
CPSF7
|
cleavage and polyadenylation specific factor 7, 59kDa
|
-2.26835
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.18685
|
|
NUDT11
|
nudix (nucleoside diphosphate linked moiety X)-type motif 11
|
-2.07755
|
|
MAFB
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
|
-2.06665
|
|
DMRT1
|
doublesex and mab-3 related transcription factor 1
|
-2.01545
|
