| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 3,3'-dimethylbenzidine.2hcl 40.4 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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75 genes differentially expressed following the CRCGN008_HEPG2_24H:P13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAGE3 | L antigen family, member 3 | 5.0714 |
| CBR3 | carbonyl reductase 3 | 4.95265 |
| E2F2 | E2F transcription factor 2 | 4.61285 |
| ADRB2 | adrenoceptor beta 2, surface | 4.2242 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.7293 |
| STIMATE | STIM activating enhancer | 3.6756 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.6418 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.54792 |
| CYCS | cytochrome c, somatic | 3.48135 |
| LOC122526780 | uncharacterized LOC122526780 | 3.3904 |
| HYOU1 | hypoxia up-regulated 1 | 3.36995 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.2847 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.98892 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 2.75125 |
| CCNF | cyclin F | 2.742 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.63545 |
| CHEK2 | checkpoint kinase 2 | 2.58775 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 2.33015 |
| CDC6 | cell division cycle 6 | 2.32877 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.31755 |
| GATA4 | GATA binding protein 4 | 2.30295 |
| RBM38 | RNA binding motif protein 38 | 2.2763 |
| CERS2 | ceramide synthase 2 | 2.2718 |
| KIAA0930 | KIAA0930 | 2.24948 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.23995 |
| RNF208 | ring finger protein 208 | 2.21215 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.20425 |
| TRAPPC2L | trafficking protein particle complex 2-like | 2.19925 |
| THOP1 | thimet oligopeptidase 1 | 2.1971 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 | 2.1892 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.1888 |
| HMGB3 | high mobility group box 3 | 2.1844 |
| RPL10L | ribosomal protein L10-like | 2.1465 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.13925 |
| TXNRD1 | thioredoxin reductase 1 | 2.12755 |
| NADSYN1 | NAD synthetase 1 | 2.1162 |
| LRRC8E | leucine rich repeat containing 8 family, member E | 2.0868 |
| ZBED1 | zinc finger, BED-type containing 1 | 2.05945 |
| IRX4 | iroquois homeobox 4 | 2.0256 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | 2.01925 |
| CERS1 | ceramide synthase 1 | 2.01725 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 2.008 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| CCNB2 | cyclin B2 | -9.1991 |
| INPP1 | inositol polyphosphate-1-phosphatase | -5.5902 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.24535 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.0 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.8058 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.66275 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.30515 |
| PCNA | proliferating cell nuclear antigen | -4.2674 |
| RAI14 | retinoic acid induced 14 | -4.2362 |
| NGRN | neugrin, neurite outgrowth associated | -4.1543 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.9173 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -3.85645 |
| RHEB | Ras homolog enriched in brain | -3.70845 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.5581 |
| GNAS | GNAS complex locus | -3.37533 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.3264 |
| PEG10 | paternally expressed 10 | -3.12407 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.9578 |
| PVALB | parvalbumin | -2.61955 |
| KLHL3 | kelch-like family member 3 | -2.52815 |
| EFHD2 | EF-hand domain family, member D2 | -2.5093 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.42768 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.3739 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -2.30615 |
| IFT57 | intraflagellar transport 57 | -2.2898 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit | -2.25775 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -2.23265 |
| CDC25B | cell division cycle 25B | -2.17895 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 | -2.11715 |
| CLIC5 | chloride intracellular channel 5 | -2.0527 |
| GHITM | growth hormone inducible transmembrane protein | -2.038 |
| SH3GL2 | SH3-domain GRB2-like 2 | -2.0236 |
