| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 3,3'-dimethylbenzidine.2hcl 5.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN008_HEPG2_24H:P16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 5.40735 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.09295 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.9976 |
| CBR3 | carbonyl reductase 3 | 4.6311 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.2793 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.9548 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.81367 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 3.4323 |
| CYCS | cytochrome c, somatic | 3.3927 |
| PRR15L | proline rich 15-like | 3.29815 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.17525 |
| GATA2 | GATA binding protein 2 | 3.15182 |
| GPATCH8 | G patch domain containing 8 | 3.10868 |
| CHEK2 | checkpoint kinase 2 | 2.97405 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.86955 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.85153 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.78772 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.692 |
| NUP133 | nucleoporin 133kDa | 2.6831 |
| HEBP1 | heme binding protein 1 | 2.61585 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.56525 |
| ZFP36 | ZFP36 ring finger protein | 2.4959 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.4333 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.37025 |
| ZNF589 | zinc finger protein 589 | 2.26417 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.2323 |
| NOSIP | nitric oxide synthase interacting protein | 2.10235 |
| ABHD4 | abhydrolase domain containing 4 | 2.0758 |
| NUCB2 | nucleobindin 2 | 2.03475 |
| STIMATE | STIM activating enhancer | 2.0308 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 2.02005 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -4.89725 |
| CDC20 | cell division cycle 20 | -4.66275 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.37975 |
| GNAS | GNAS complex locus | -3.79144 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -3.6855 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.5949 |
| ZNF274 | zinc finger protein 274 | -3.51495 |
| DCK | deoxycytidine kinase | -3.3159 |
| CD58 | CD58 molecule | -3.1746 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -3.1376 |
| CLIC4 | chloride intracellular channel 4 | -3.10082 |
| PDZD2 | PDZ domain containing 2 | -3.0366 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.0031 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.00178 |
| MTA1 | metastasis associated 1 | -2.9502 |
| SESN1 | sestrin 1 | -2.63275 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.61923 |
| DRD1 | dopamine receptor D1 | -2.61365 |
| HSPA8 | heat shock 70kDa protein 8 | -2.45835 |
| NPHP1 | nephronophthisis 1 (juvenile) | -2.34155 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.32185 |
| PCDHA9 | protocadherin alpha 9 | -2.2822 |
| NVL | nuclear VCP-like | -2.27465 |
| HAO2 | hydroxyacid oxidase 2 (long chain) | -2.2624 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.2469 |
| FASLG | Fas ligand (TNF superfamily, member 6) | -2.20875 |
| PCDH8 | protocadherin 8 | -2.144 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.1375 |
| STYK1 | serine/threonine/tyrosine kinase 1 | -2.13555 |
| ZW10 | zw10 kinetochore protein | -2.09995 |
| SORCS3 | sortilin-related VPS10 domain containing receptor 3 | -2.0899 |
| GDF10 | growth differentiation factor 10 | -2.0581 |
| PRMT8 | protein arginine methyltransferase 8 | -2.04975 |
| GPR88 | G protein-coupled receptor 88 | -2.0308 |
| ADAM23 | ADAM metallopeptidase domain 23 | -2.02295 |
| BRME1 | break repair meiotic recombinase recruitment factor 1 | -2.01045 |
| IFNW1 | interferon, omega 1 | -2.0034 |
| TSPYL4 | TSPY-like 4 | -2.00335 |
