CRCGN008_HEPG2_24H:P17 Gene Set
Genes
50 genes differentially expressed following the CRCGN008_HEPG2_24H:P17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
5.74985
|
|
CCNF
|
cyclin F
|
5.59475
|
|
MYLK
|
myosin light chain kinase
|
5.5866
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.3361
|
|
KIFBP
|
kinesin family binding protein
|
5.12995
|
|
CBR3
|
carbonyl reductase 3
|
4.81885
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
4.7973
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.42305
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
4.1414
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.83792
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.431
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.30433
|
|
CHN1
|
chimerin 1
|
3.15175
|
|
EGF
|
epidermal growth factor
|
3.12175
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.0816
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.77075
|
|
KIF20A
|
kinesin family member 20A
|
2.67925
|
|
JADE2
|
jade family PHD finger 2
|
2.6566
|
|
TBPL1
|
TBP-like 1
|
2.56945
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.29845
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.2831
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.2678
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.259
|
|
HEBP1
|
heme binding protein 1
|
2.2266
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
2.21213
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.08415
|
|
SCRN1
|
secernin 1
|
2.02655
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-7.29765
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-5.7102
|
|
CCNB2
|
cyclin B2
|
-4.8094
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.80405
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.70805
|
|
VAT1
|
vesicle amine transport 1
|
-4.4148
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-4.28145
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.12495
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.3038
|
|
CLIC4
|
chloride intracellular channel 4
|
-3.28263
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.02215
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.9109
|
|
MTA1
|
metastasis associated 1
|
-2.7822
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
-2.7703
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.59465
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-2.5771
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-2.4751
|
|
LSM6
|
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.28525
|
|
WASHC4
|
WASH complex subunit 4
|
-2.2575
|
|
CDC25B
|
cell division cycle 25B
|
-2.18545
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.06315
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.05105
|
|
ATXN3
|
ataxin 3
|
-2.03385
|