| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nitrosoethylmethylamine 39.4 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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78 genes differentially expressed following the CRCGN008_HEPG2_24H:P19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HEBP1 | heme binding protein 1 | 6.52955 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 6.42485 |
| ADRB2 | adrenoceptor beta 2, surface | 5.4598 |
| CCNA1 | cyclin A1 | 5.42835 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.36225 |
| TATDN2 | TatD DNase domain containing 2 | 5.15885 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.94233 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.90085 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.85875 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.8555 |
| STIMATE | STIM activating enhancer | 4.6083 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.06055 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.93957 |
| TXNL4B | thioredoxin-like 4B | 3.89175 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 3.61181 |
| CDCA4 | cell division cycle associated 4 | 3.3168 |
| CYCS | cytochrome c, somatic | 3.2928 |
| PTK2 | protein tyrosine kinase 2 | 3.27025 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.21405 |
| NLRP2B | NLR family pyrin domain containing 2B | 3.21275 |
| CHN1 | chimerin 1 | 3.1116 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 3.07995 |
| CCNF | cyclin F | 3.0135 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.8839 |
| ZNF589 | zinc finger protein 589 | 2.87693 |
| CERT1 | ceramide transporter 1 | 2.6475 |
| TLR4 | toll-like receptor 4 | 2.4869 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.43245 |
| TAC4 | tachykinin 4 (hemokinin) | 2.42175 |
| GATA4 | GATA binding protein 4 | 2.40225 |
| EPHA3 | EPH receptor A3 | 2.36488 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.34663 |
| NISCH | nischarin | 2.3022 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.27425 |
| TBX3 | T-box 3 | 2.2187 |
| EVL | Enah/Vasp-like | 2.21155 |
| MBNL2 | muscleblind-like splicing regulator 2 | 2.13602 |
| AGO4 | argonaute RISC catalytic component 4 | 2.08585 |
| MKRN2 | makorin ring finger protein 2 | 2.07985 |
| APOC3 | apolipoprotein C-III | 2.07695 |
| RFTN1 | raftlin, lipid raft linker 1 | 2.0691 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.06295 |
| ZNF232 | zinc finger protein 232 | 2.0622 |
| NID1 | nidogen 1 | 2.05043 |
| LOC122526780 | uncharacterized LOC122526780 | 2.04375 |
| FMO3 | flavin containing monooxygenase 3 | 2.00528 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.3194 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.79715 |
| LDHD | lactate dehydrogenase D | -4.7281 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.62575 |
| PCNA | proliferating cell nuclear antigen | -4.50795 |
| GLOD4 | glyoxalase domain containing 4 | -4.1483 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -4.0546 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.99795 |
| SLC35F2 | solute carrier family 35, member F2 | -3.5852 |
| ZNF274 | zinc finger protein 274 | -3.2232 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -3.1668 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.06792 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.88065 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.7561 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.68478 |
| ICAM3 | intercellular adhesion molecule 3 | -2.6803 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.62603 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.6063 |
| HSPA8 | heat shock 70kDa protein 8 | -2.57572 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.5165 |
| RBM15B | RNA binding motif protein 15B | -2.49885 |
| CTSD | cathepsin D | -2.43745 |
| TXNDC9 | thioredoxin domain containing 9 | -2.42657 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.3772 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.35955 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.2982 |
| BABAM1 | BRISC and BRCA1 A complex member 1 | -2.27695 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.227 |
| SIN3B | SIN3 transcription regulator family member B | -2.13762 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.11035 |
| DDA1 | DET1 and DDB1 associated 1 | -2.04495 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | -2.03325 |
