| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nitrosoethylmethylamine 19.7 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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84 genes differentially expressed following the CRCGN008_HEPG2_24H:P20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.36885 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.97305 |
| E2F2 | E2F transcription factor 2 | 4.8026 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.7272 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.68555 |
| RPL39L | ribosomal protein L39-like | 4.63915 |
| EPN2 | epsin 2 | 4.54855 |
| UBQLN2 | ubiquilin 2 | 4.54165 |
| MCOLN1 | mucolipin 1 | 4.46515 |
| PRR15L | proline rich 15-like | 4.2457 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.0446 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.98565 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.97135 |
| GATA3 | GATA binding protein 3 | 3.75423 |
| CCNA1 | cyclin A1 | 3.74675 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.69868 |
| FZD7 | frizzled class receptor 7 | 3.6154 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.26315 |
| BIRC2 | baculoviral IAP repeat containing 2 | 3.2562 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 3.17045 |
| MAP7 | microtubule-associated protein 7 | 2.97303 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.8651 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.76533 |
| TBP | TATA box binding protein | 2.6194 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.53978 |
| SAYSD1 | SAYSVFN motif domain containing 1 | 2.481 |
| HEBP1 | heme binding protein 1 | 2.41875 |
| EPHA3 | EPH receptor A3 | 2.41033 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.3382 |
| PKN1 | protein kinase N1 | 2.3104 |
| EFNA1 | ephrin-A1 | 2.2875 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.2631 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 2.2238 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.209 |
| CD101 | CD101 molecule | 2.16095 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 2.1416 |
| KRT7 | keratin 7, type II | 2.1334 |
| PINLYP | phospholipase A2 inhibitor and LY6/PLAUR domain containing | 2.12785 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.07655 |
| CEP57 | centrosomal protein 57kDa | 2.03961 |
| CYCS | cytochrome c, somatic | 2.0304 |
| TRMT61B | tRNA methyltransferase 61B | 2.02175 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2.02128 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -5.54445 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -5.2508 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -5.1641 |
| EGF | epidermal growth factor | -5.06085 |
| CDC20 | cell division cycle 20 | -5.0 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.81315 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.78895 |
| CD320 | CD320 molecule | -4.77915 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.7015 |
| ADI1 | acireductone dioxygenase 1 | -4.50955 |
| TLCD3A | TLC domain containing 3A | -4.47925 |
| YME1L1 | YME1-like 1 ATPase | -4.44862 |
| SLC35F2 | solute carrier family 35, member F2 | -4.4442 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.1171 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.6129 |
| CDC25B | cell division cycle 25B | -3.5887 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.8848 |
| BHMT | betaine--homocysteine S-methyltransferase | -2.77565 |
| PYGB | phosphorylase, glycogen; brain | -2.6373 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.50345 |
| SOAT2 | sterol O-acyltransferase 2 | -2.4498 |
| GDF15 | growth differentiation factor 15 | -2.40255 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.32675 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.31075 |
| RHOA | ras homolog family member A | -2.22358 |
| HMGB2 | high mobility group box 2 | -2.21595 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | -2.19825 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.1982 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.1845 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.1629 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -2.14365 |
| AHSP | alpha hemoglobin stabilizing protein | -2.13665 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | -2.11195 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -2.06485 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) | -2.0608 |
| HBD | hemoglobin, delta | -2.03955 |
| MOSPD1 | motile sperm domain containing 1 | -2.0116 |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 | -2.00975 |
| RFPL3 | ret finger protein-like 3 | -2.0075 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -2.0068 |
| ABHD17A | abhydrolase domain containing 17A | -2.0042 |
