| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nitrosoethylmethylamine 9.85 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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82 genes differentially expressed following the CRCGN008_HEPG2_24H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 6.05805 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.51845 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.2797 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.15475 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.6178 |
| LSR | lipolysis stimulated lipoprotein receptor | 4.524 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 4.48745 |
| NUP133 | nucleoporin 133kDa | 4.19455 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.03003 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 3.8544 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.67435 |
| PMM2 | phosphomannomutase 2 | 3.44425 |
| SATB1 | SATB homeobox 1 | 3.3116 |
| ABHD4 | abhydrolase domain containing 4 | 3.0056 |
| KIF20A | kinesin family member 20A | 2.9835 |
| SMAD3 | SMAD family member 3 | 2.91675 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.8803 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 2.77525 |
| SQOR | sulfide quinone oxidoreductase | 2.6578 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.64245 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.58645 |
| WASF3 | WAS protein family, member 3 | 2.5174 |
| RBM34 | RNA binding motif protein 34 | 2.43337 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.42405 |
| ZNF589 | zinc finger protein 589 | 2.3918 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.37665 |
| RAB21 | RAB21, member RAS oncogene family | 2.36625 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.26165 |
| PHF20L1 | PHD finger protein 20-like 1 | 2.2573 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.2548 |
| NUCB2 | nucleobindin 2 | 2.2314 |
| ITM2C | integral membrane protein 2C | 2.201 |
| BAX | BCL2-associated X protein | 2.20083 |
| MAT2A | methionine adenosyltransferase II, alpha | 2.16008 |
| ISOC1 | isochorismatase domain containing 1 | 2.15025 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 2.13265 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 2.0835 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.05713 |
| TDG | thymine-DNA glycosylase | 2.05645 |
| SYNM | synemin, intermediate filament protein | 2.05425 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 2.04163 |
| EXOC2 | exocyst complex component 2 | 2.03875 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 2.0162 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 2.00685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.6424 |
| DCK | deoxycytidine kinase | -6.36005 |
| CD320 | CD320 molecule | -5.3667 |
| GTPBP8 | GTP-binding protein 8 (putative) | -5.0812 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7331 |
| USP6NL | USP6 N-terminal like | -4.51475 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -3.95395 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -3.75647 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.6941 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.58435 |
| CD58 | CD58 molecule | -3.30795 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -3.19805 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -3.14215 |
| ICAM3 | intercellular adhesion molecule 3 | -3.0105 |
| ATG14 | autophagy related 14 | -2.89105 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -2.7406 |
| RGS2 | regulator of G-protein signaling 2 | -2.65785 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.5653 |
| WDR83OS | WD repeat domain 83 opposite strand | -2.48165 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.3637 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.34997 |
| COG7 | component of oligomeric golgi complex 7 | -2.28345 |
| GLI3 | GLI family zinc finger 3 | -2.2756 |
| KIF1A | kinesin family member 1A | -2.27245 |
| FAM171A1 | family with sequence similarity 171, member A1 | -2.19235 |
| HYOU1 | hypoxia up-regulated 1 | -2.1823 |
| DZIP1 | DAZ interacting zinc finger protein 1 | -2.14345 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -2.12187 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.10365 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -2.0729 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -2.04335 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -2.03235 |
| ZFP91 | ZFP91 zinc finger protein | -2.03005 |
| BMP4 | bone morphogenetic protein 4 | -2.01545 |
| STRA6 | stimulated by retinoic acid 6 | -2.0146 |
| MAPT | microtubule-associated protein tau | -2.00596 |
| TMEM267 | transmembrane protein 267 | -2.00015 |
