CRCGN008_HEPG2_24H:P22 Gene Set
Genes
54 genes differentially expressed following the CRCGN008_HEPG2_24H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHEK2
|
checkpoint kinase 2
|
5.4054
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.2787
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.2112
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
5.1752
|
|
TATDN2
|
TatD DNase domain containing 2
|
5.1215
|
|
UBQLN2
|
ubiquilin 2
|
5.03015
|
|
CBR3
|
carbonyl reductase 3
|
4.83305
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.792
|
|
CHN1
|
chimerin 1
|
4.54485
|
|
EGF
|
epidermal growth factor
|
4.05595
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.87603
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
3.70602
|
|
MAP7
|
microtubule-associated protein 7
|
3.21912
|
|
HEBP1
|
heme binding protein 1
|
3.19115
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
3.1825
|
|
ZNF589
|
zinc finger protein 589
|
3.1509
|
|
RB1
|
retinoblastoma 1
|
3.11002
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.06025
|
|
CEP57
|
centrosomal protein 57kDa
|
3.00816
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.89218
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.75323
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.60203
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.4999
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.4687
|
|
EPHA3
|
EPH receptor A3
|
2.40637
|
|
CYCS
|
cytochrome c, somatic
|
2.29055
|
|
SETD5
|
SET domain containing 5
|
2.2075
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.1657
|
|
EFL1
|
elongation factor like GTPase 1
|
2.0929
|
|
CPB1
|
carboxypeptidase B1 (tissue)
|
2.05605
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-5.62735
|
|
PSMD2
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
|
-4.7981
|
|
ZNF586
|
zinc finger protein 586
|
-4.6667
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.50675
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.4286
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.92645
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.84888
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.76925
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.6438
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-3.3478
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.24078
|
|
RNF167
|
ring finger protein 167
|
-3.04745
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-3.01772
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.88835
|
|
STAT4
|
signal transducer and activator of transcription 4
|
-2.81005
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.36585
|
|
AP2M1
|
adaptor-related protein complex 2, mu 1 subunit
|
-2.33175
|
|
USP21
|
ubiquitin specific peptidase 21
|
-2.209
|
|
RIC8A
|
RIC8 guanine nucleotide exchange factor A
|
-2.1802
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.14357
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.0988
|
|
SLAMF7
|
SLAM family member 7
|
-2.03015
|
|
SMIM44
|
small integral membrane protein 44
|
-2.0042
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-2.0
|
