| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nitrosoethylmethylamine 2.46 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN008_HEPG2_24H:P23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 5.5658 |
| BAX | BCL2-associated X protein | 5.42013 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.1845 |
| NOTCH1 | notch 1 | 5.179 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.6545 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.38435 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.2988 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.20565 |
| ABHD4 | abhydrolase domain containing 4 | 3.86115 |
| CHN1 | chimerin 1 | 3.8317 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.50785 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 3.2542 |
| SFTPB | surfactant protein B | 3.16622 |
| TBXA2R | thromboxane A2 receptor | 3.1451 |
| NUP133 | nucleoporin 133kDa | 2.97245 |
| PFKL | phosphofructokinase, liver | 2.96407 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.85873 |
| TRIM13 | tripartite motif containing 13 | 2.76795 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.76175 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.74275 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.55355 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.5188 |
| FOXO3 | forkhead box O3 | 2.39651 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.38695 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.3349 |
| ZFP36 | ZFP36 ring finger protein | 2.29595 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.21865 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 2.18517 |
| STXBP2 | syntaxin binding protein 2 | 2.1701 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | 2.14405 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | 2.12652 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 | 2.1111 |
| ECD | ecdysoneless homolog (Drosophila) | 2.10295 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.09895 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.0727 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.00778 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLCD3A | TLC domain containing 3A | -5.5246 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.45355 |
| BLCAP | bladder cancer associated protein | -5.31465 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.0 |
| PCNA | proliferating cell nuclear antigen | -4.77245 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.68575 |
| LDHD | lactate dehydrogenase D | -4.6787 |
| ADI1 | acireductone dioxygenase 1 | -4.6019 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.36165 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -4.3299 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -3.9922 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -3.9449 |
| FASTKD5 | FAST kinase domains 5 | -3.8421 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.8228 |
| CD58 | CD58 molecule | -3.59023 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.38707 |
| CLTB | clathrin, light chain B | -3.32 |
| DCK | deoxycytidine kinase | -3.0186 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.9256 |
| PDZD2 | PDZ domain containing 2 | -2.84798 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -2.79997 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.6174 |
| ZW10 | zw10 kinetochore protein | -2.5039 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.48327 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 | -2.1758 |
| CDC25B | cell division cycle 25B | -2.1574 |
| KIF16B | kinesin family member 16B | -2.1066 |
| HMG20B | high mobility group 20B | -2.1054 |
| SMC3 | structural maintenance of chromosomes 3 | -2.0933 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -2.0911 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -2.07835 |
| PYGB | phosphorylase, glycogen; brain | -2.07205 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.05865 |
| KLHDC8A | kelch domain containing 8A | -2.01065 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.00045 |
