| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nitrosoethylmethylamine 1.23 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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77 genes differentially expressed following the CRCGN008_HEPG2_24H:P24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 5.1294 |
| JADE2 | jade family PHD finger 2 | 4.9339 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.92265 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.913 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.85615 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 4.4912 |
| NOSIP | nitric oxide synthase interacting protein | 4.4488 |
| ABHD6 | abhydrolase domain containing 6 | 4.448 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.3366 |
| STK10 | serine/threonine kinase 10 | 4.26745 |
| PIH1D1 | PIH1 domain containing 1 | 4.2442 |
| MAMLD1 | mastermind-like domain containing 1 | 4.23545 |
| PRR15L | proline rich 15-like | 4.2341 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.9444 |
| HOXA10 | homeobox A10 | 3.89482 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.50693 |
| EGF | epidermal growth factor | 3.41135 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.9111 |
| CHN1 | chimerin 1 | 2.6325 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.5962 |
| IL17RB | interleukin 17 receptor B | 2.4099 |
| PMM2 | phosphomannomutase 2 | 2.39855 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.33455 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.26793 |
| TXNL4B | thioredoxin-like 4B | 2.26685 |
| HOXA11 | homeobox A11 | 2.2486 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 2.24075 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.21375 |
| PDZK1 | PDZ domain containing 1 | 2.18875 |
| RCOR1 | REST corepressor 1 | 2.1578 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 2.153 |
| CALB1 | calbindin 1, 28kDa | 2.1214 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 | 2.0908 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 2.04775 |
| PKDREJ | polycystin (PKD) family receptor for egg jelly | 2.04675 |
| HOXC10 | homeobox C10 | 2.0387 |
| RAB17 | RAB17, member RAS oncogene family | 2.02975 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 2.00845 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COG2 | component of oligomeric golgi complex 2 | -4.77065 |
| FAIM | Fas apoptotic inhibitory molecule | -4.74925 |
| ADI1 | acireductone dioxygenase 1 | -4.5376 |
| LDHD | lactate dehydrogenase D | -4.4676 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -4.15882 |
| TLCD3A | TLC domain containing 3A | -3.86085 |
| TMEM109 | transmembrane protein 109 | -3.84855 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.7162 |
| CCNB2 | cyclin B2 | -3.6294 |
| GNAS | GNAS complex locus | -3.56491 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.3757 |
| SPAG4 | sperm associated antigen 4 | -3.2954 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -3.16945 |
| TWF2 | twinfilin actin binding protein 2 | -2.9891 |
| ZNF586 | zinc finger protein 586 | -2.87215 |
| CAB39L | calcium binding protein 39-like | -2.4069 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -2.39495 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.37865 |
| AHNAK2 | AHNAK nucleoprotein 2 | -2.3631 |
| ATP9A | ATPase, class II, type 9A | -2.3379 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.3334 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -2.3214 |
| NVL | nuclear VCP-like | -2.31415 |
| SAYSD1 | SAYSVFN motif domain containing 1 | -2.27775 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.23575 |
| CLTB | clathrin, light chain B | -2.23439 |
| ZNF274 | zinc finger protein 274 | -2.22635 |
| CHRFAM7A | CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion | -2.19985 |
| ACKR3 | atypical chemokine receptor 3 | -2.15375 |
| PRDM14 | PR domain containing 14 | -2.13895 |
| CDC25B | cell division cycle 25B | -2.12335 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.123 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 | -2.11905 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -2.09825 |
| REEP5 | receptor accessory protein 5 | -2.09688 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.0492 |
| RBM15B | RNA binding motif protein 15B | -2.04465 |
| DUOX2 | dual oxidase 2 | -2.02825 |
| COL8A2 | collagen, type VIII, alpha 2 | -2.01655 |
