CRCGN009_HEPG2_24H:A03 Gene Set
Genes
52 genes differentially expressed following the CRCGN009_HEPG2_24H:A03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.78263
|
|
PRKCH
|
protein kinase C, eta
|
5.01542
|
|
UBQLN2
|
ubiquilin 2
|
4.45495
|
|
EPHB2
|
EPH receptor B2
|
4.1257
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.87891
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.84496
|
|
VGLL4
|
vestigial-like family member 4
|
3.70535
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.09901
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
3.08886
|
|
GPATCH8
|
G patch domain containing 8
|
2.98828
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.93045
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.84606
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.82509
|
|
SATB1
|
SATB homeobox 1
|
2.75801
|
|
LOXL1
|
lysyl oxidase-like 1
|
2.63661
|
|
CHN1
|
chimerin 1
|
2.39429
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.36234
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.25785
|
|
PMM2
|
phosphomannomutase 2
|
2.07911
|
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
|
2.04333
|
|
CCNJ
|
cyclin J
|
2.00916
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB1
|
cyclin B1
|
-5.55469
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.84274
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.5565
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.29571
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.92497
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.63156
|
|
CCNB2
|
cyclin B2
|
-3.52701
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.51375
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.32434
|
|
LDHD
|
lactate dehydrogenase D
|
-3.19237
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.1631
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.02713
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.93921
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.87958
|
|
TCTN1
|
tectonic family member 1
|
-2.7605
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.52084
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-2.49675
|
|
LYPLA1
|
lysophospholipase I
|
-2.47832
|
|
TLR4
|
toll-like receptor 4
|
-2.40329
|
|
NUP85
|
nucleoporin 85kDa
|
-2.39718
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.34889
|
|
DNM1L
|
dynamin 1-like
|
-2.26901
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.26521
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.23402
|
|
SNX11
|
sorting nexin 11
|
-2.22788
|
|
GNAS
|
GNAS complex locus
|
-2.21875
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.16837
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.15682
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-2.13106
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.08941
|
|
GRB2
|
growth factor receptor-bound protein 2
|
-2.04588
|
