CRCGN009_HEPG2_24H:A04 Gene Set
Genes
49 genes differentially expressed following the CRCGN009_HEPG2_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
4.80772
|
|
CYCS
|
cytochrome c, somatic
|
4.65127
|
|
HOXA10
|
homeobox A10
|
4.10502
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.9869
|
|
UBQLN2
|
ubiquilin 2
|
3.93846
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.7321
|
|
MYLK
|
myosin light chain kinase
|
3.37389
|
|
TATDN2
|
TatD DNase domain containing 2
|
3.29593
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
3.21749
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
3.19222
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.18474
|
|
RPL39L
|
ribosomal protein L39-like
|
3.10085
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.02948
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.95758
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.92596
|
|
MOK
|
MOK protein kinase
|
2.82433
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.8045
|
|
LCN2
|
lipocalin 2
|
2.65821
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.60953
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.56064
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.49438
|
|
INTS3
|
integrator complex subunit 3
|
2.44647
|
|
ELAC2
|
elaC ribonuclease Z 2
|
2.3281
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.22148
|
|
POLA2
|
polymerase (DNA directed), alpha 2, accessory subunit
|
2.18164
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.15857
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.02915
|
|
RPS6KB1
|
ribosomal protein S6 kinase, 70kDa, polypeptide 1
|
2.01278
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-5.38073
|
|
GNAS
|
GNAS complex locus
|
-5.32477
|
|
ZNF586
|
zinc finger protein 586
|
-5.02679
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.87495
|
|
VAT1
|
vesicle amine transport 1
|
-3.3473
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-3.18378
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-3.10881
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.02843
|
|
CDC20
|
cell division cycle 20
|
-3.01971
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.89621
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.8958
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.87875
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.844
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.82368
|
|
CD320
|
CD320 molecule
|
-2.45157
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.20075
|
|
FBXO7
|
F-box protein 7
|
-2.07827
|
|
SRRD
|
SRR1 domain containing
|
-2.07444
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.07153
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.06446
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.00476
|
