| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | propyl gallate 19.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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96 genes differentially expressed following the CRCGN009_HEPG2_24H:A08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABHD4 | abhydrolase domain containing 4 | 8.61697 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 6.48663 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 6.14389 |
| TXNRD1 | thioredoxin reductase 1 | 5.87781 |
| UGDH | UDP-glucose 6-dehydrogenase | 5.22958 |
| ABHD6 | abhydrolase domain containing 6 | 3.52264 |
| HMOX1 | heme oxygenase 1 | 3.47338 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 3.36699 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.3248 |
| NOTCH1 | notch 1 | 3.26669 |
| INTS3 | integrator complex subunit 3 | 3.25628 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.18886 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.1852 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.16783 |
| STIMATE | STIM activating enhancer | 3.06771 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 3.01227 |
| EVL | Enah/Vasp-like | 3.01145 |
| KEAP1 | kelch-like ECH-associated protein 1 | 2.93817 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.81313 |
| SFTPB | surfactant protein B | 2.79106 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 2.77314 |
| CTSL | cathepsin L | 2.77286 |
| NUCB2 | nucleobindin 2 | 2.56519 |
| SATB1 | SATB homeobox 1 | 2.51524 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.45468 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.4247 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.4099 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.39338 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 2.37915 |
| SQSTM1 | sequestosome 1 | 2.36908 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.35909 |
| PMM2 | phosphomannomutase 2 | 2.3057 |
| RPN1 | ribophorin I | 2.30437 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.26262 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.17848 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 2.17249 |
| PAQR4 | progestin and adipoQ receptor family member IV | 2.16686 |
| PLPP2 | phospholipid phosphatase 2 | 2.15784 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.12833 |
| TMEM50A | transmembrane protein 50A | 2.12635 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.11974 |
| PRR15L | proline rich 15-like | 2.0886 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 2.07143 |
| SIRT3 | sirtuin 3 | 2.07034 |
| GOLGB1 | golgin B1 | 2.06752 |
| KIF20A | kinesin family member 20A | 2.03384 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 2.00532 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.69314 |
| SLC35F2 | solute carrier family 35, member F2 | -4.61726 |
| DNM1L | dynamin 1-like | -4.33566 |
| VAT1 | vesicle amine transport 1 | -3.61536 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -3.59816 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.58418 |
| CD320 | CD320 molecule | -3.47611 |
| CDC20 | cell division cycle 20 | -3.39936 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.39432 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.30819 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -3.26472 |
| PRPF4 | pre-mRNA processing factor 4 | -3.15366 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.14049 |
| RSU1 | Ras suppressor protein 1 | -3.13038 |
| YME1L1 | YME1-like 1 ATPase | -3.08652 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.01998 |
| MRPL42 | mitochondrial ribosomal protein L42 | -3.01437 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.8098 |
| SPAG4 | sperm associated antigen 4 | -2.80442 |
| CDK1 | cyclin-dependent kinase 1 | -2.75878 |
| MYL9 | myosin, light chain 9, regulatory | -2.65603 |
| PLK1 | polo-like kinase 1 | -2.6175 |
| SNX11 | sorting nexin 11 | -2.56512 |
| DIABLO | diablo, IAP-binding mitochondrial protein | -2.50753 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -2.4816 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.4761 |
| CCDC85B | coiled-coil domain containing 85B | -2.45709 |
| INPP1 | inositol polyphosphate-1-phosphatase | -2.42563 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.39467 |
| HAT1 | histone acetyltransferase 1 | -2.28579 |
| WASHC4 | WASH complex subunit 4 | -2.24305 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | -2.21355 |
| BCAP29 | B-cell receptor-associated protein 29 | -2.19733 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.1801 |
| TUBB6 | tubulin, beta 6 class V | -2.17237 |
| TPM4 | tropomyosin 4 | -2.15279 |
| SNX6 | sorting nexin 6 | -2.12884 |
| NISCH | nischarin | -2.12281 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -2.11016 |
| TOR1A | torsin family 1, member A (torsin A) | -2.11 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.10451 |
| IER3 | immediate early response 3 | -2.09644 |
| HEMK2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | -2.08466 |
| CCNA2 | cyclin A2 | -2.0802 |
| ICAM1 | intercellular adhesion molecule 1 | -2.05576 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.04392 |
| MRPL39 | mitochondrial ribosomal protein L39 | -2.03597 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -2.0301 |
