CRCGN009_HEPG2_24H:A09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyl gallate 9.95 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

64 genes differentially expressed following the CRCGN009_HEPG2_24H:A09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 6.97721
RPP38 ribonuclease P/MRP 38kDa subunit 6.4286
UGDH UDP-glucose 6-dehydrogenase 5.81501
TXNRD1 thioredoxin reductase 1 5.74792
ABHD4 abhydrolase domain containing 4 5.4676
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.24747
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.14287
STIMATE STIM activating enhancer 3.8493
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.75228
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.74594
MYLK myosin light chain kinase 3.7319
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.58351
CCL2 chemokine (C-C motif) ligand 2 3.54848
NUCB2 nucleobindin 2 3.37044
ABHD6 abhydrolase domain containing 6 3.16007
KEAP1 kelch-like ECH-associated protein 1 3.09385
UBQLN2 ubiquilin 2 3.0299
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.97688
PPARG peroxisome proliferator-activated receptor gamma 2.71441
EPN2 epsin 2 2.68359
HMOX1 heme oxygenase 1 2.64039
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.58391
CYCS cytochrome c, somatic 2.5076
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.36586
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.3566
EAPP E2F-associated phosphoprotein 2.30235
MEPCE methylphosphate capping enzyme 2.27938
JADE1 jade family PHD finger 1 2.18847
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.15599
SETD5 SET domain containing 5 2.13125
HOOK2 hook microtubule-tethering protein 2 2.11795
GPER1 G protein-coupled estrogen receptor 1 2.09394
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 2.09094
CNPY3 canopy FGF signaling regulator 3 2.08164
CCNF cyclin F 2.07421
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.0539
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.04816
FLRT1 fibronectin leucine rich transmembrane protein 1 2.03703
BLMH bleomycin hydrolase 2.02964
TMED1 transmembrane emp24 protein transport domain containing 1 2.0048

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -9.51664
ZNF586 zinc finger protein 586 -6.72751
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -6.53773
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.84133
RPIA ribose 5-phosphate isomerase A -4.47062
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.77239
GOLT1B golgi transport 1B -3.52029
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.27916
CDC20 cell division cycle 20 -3.24454
OXA1L oxidase (cytochrome c) assembly 1-like -3.24152
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.15249
CCNB2 cyclin B2 -2.97356
DNM1L dynamin 1-like -2.70956
LDHD lactate dehydrogenase D -2.69981
MAPK13 mitogen-activated protein kinase 13 -2.50846
RAI14 retinoic acid induced 14 -2.39466
TUBB6 tubulin, beta 6 class V -2.38075
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.3799
NRIP1 nuclear receptor interacting protein 1 -2.27488
CAPN1 calpain 1, (mu/I) large subunit -2.22741
IER3 immediate early response 3 -2.17872
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.13023
DEF8 differentially expressed in FDCP 8 homolog (mouse) -2.08358
INPP1 inositol polyphosphate-1-phosphatase -2.02956