| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | propyl gallate 4.98 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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55 genes differentially expressed following the CRCGN009_HEPG2_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 5.72826 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 4.09673 |
| ABHD4 | abhydrolase domain containing 4 | 3.81518 |
| MOK | MOK protein kinase | 3.80609 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.79479 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.75885 |
| TXNRD1 | thioredoxin reductase 1 | 3.75206 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.59594 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.55078 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.50886 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.49654 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.36637 |
| UGDH | UDP-glucose 6-dehydrogenase | 3.34824 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.29178 |
| ADRB2 | adrenoceptor beta 2, surface | 3.26465 |
| RPL39L | ribosomal protein L39-like | 3.26293 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.20923 |
| UBQLN2 | ubiquilin 2 | 3.09179 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.72162 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.67468 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.45125 |
| PRR15L | proline rich 15-like | 2.44512 |
| PMM2 | phosphomannomutase 2 | 2.39193 |
| CBR3 | carbonyl reductase 3 | 2.37768 |
| LOC122526780 | uncharacterized LOC122526780 | 2.32481 |
| RHOT2 | ras homolog family member T2 | 2.20754 |
| CADPS2 | Ca++-dependent secretion activator 2 | 2.16553 |
| SIRT3 | sirtuin 3 | 2.12328 |
| BAG3 | BCL2-associated athanogene 3 | 2.08662 |
| BLMH | bleomycin hydrolase | 2.08179 |
| MAP7 | microtubule-associated protein 7 | 2.00088 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.41719 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.67099 |
| ENOPH1 | enolase-phosphatase 1 | -4.16973 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.51005 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.46215 |
| PCNA | proliferating cell nuclear antigen | -3.16037 |
| RPIA | ribose 5-phosphate isomerase A | -3.14334 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.97917 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.8532 |
| TCTN1 | tectonic family member 1 | -2.58733 |
| ACOT9 | acyl-CoA thioesterase 9 | -2.51379 |
| SNX11 | sorting nexin 11 | -2.46135 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.42303 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.34907 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.29392 |
| INPP1 | inositol polyphosphate-1-phosphatase | -2.28189 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F | -2.22344 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.13884 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.13466 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.04491 |
| EDN1 | endothelin 1 | -2.0372 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -2.02452 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -2.01795 |
| RNF167 | ring finger protein 167 | -2.00733 |