CRCGN009_HEPG2_24H:A10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyl gallate 4.98 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

55 genes differentially expressed following the CRCGN009_HEPG2_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.72826
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 4.09673
ABHD4 abhydrolase domain containing 4 3.81518
MOK MOK protein kinase 3.80609
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.79479
AMDHD2 amidohydrolase domain containing 2 3.75885
TXNRD1 thioredoxin reductase 1 3.75206
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.59594
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.55078
LPAR2 lysophosphatidic acid receptor 2 3.50886
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.49654
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.36637
UGDH UDP-glucose 6-dehydrogenase 3.34824
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.29178
ADRB2 adrenoceptor beta 2, surface 3.26465
RPL39L ribosomal protein L39-like 3.26293
SOCS2 suppressor of cytokine signaling 2 3.20923
UBQLN2 ubiquilin 2 3.09179
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.72162
CIAO3 cytosolic iron-sulfur assembly component 3 2.67468
GPER1 G protein-coupled estrogen receptor 1 2.45125
PRR15L proline rich 15-like 2.44512
PMM2 phosphomannomutase 2 2.39193
CBR3 carbonyl reductase 3 2.37768
LOC122526780 uncharacterized LOC122526780 2.32481
RHOT2 ras homolog family member T2 2.20754
CADPS2 Ca++-dependent secretion activator 2 2.16553
SIRT3 sirtuin 3 2.12328
BAG3 BCL2-associated athanogene 3 2.08662
BLMH bleomycin hydrolase 2.08179
MAP7 microtubule-associated protein 7 2.00088

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -7.41719
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -5.67099
ENOPH1 enolase-phosphatase 1 -4.16973
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.51005
ZMIZ1 zinc finger, MIZ-type containing 1 -3.46215
PCNA proliferating cell nuclear antigen -3.16037
RPIA ribose 5-phosphate isomerase A -3.14334
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.97917
ITGB1BP1 integrin beta 1 binding protein 1 -2.8532
TCTN1 tectonic family member 1 -2.58733
ACOT9 acyl-CoA thioesterase 9 -2.51379
SNX11 sorting nexin 11 -2.46135
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.42303
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.34907
NT5DC2 5'-nucleotidase domain containing 2 -2.29392
INPP1 inositol polyphosphate-1-phosphatase -2.28189
POLR2F polymerase (RNA) II (DNA directed) polypeptide F -2.22344
PCCB propionyl CoA carboxylase, beta polypeptide -2.13884
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.13466
CRELD2 cysteine-rich with EGF-like domains 2 -2.04491
EDN1 endothelin 1 -2.0372
GTF2A2 general transcription factor IIA, 2, 12kDa -2.02452
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.01795
RNF167 ring finger protein 167 -2.00733