CRCGN009_HEPG2_24H:A11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyl gallate 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

52 genes differentially expressed following the CRCGN009_HEPG2_24H:A11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 6.99302
RPL39L ribosomal protein L39-like 6.53794
GPATCH8 G patch domain containing 8 5.33114
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 5.22127
CYCS cytochrome c, somatic 4.91893
MAP7 microtubule-associated protein 7 4.76191
CHN1 chimerin 1 4.17632
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.56036
STK10 serine/threonine kinase 10 3.52391
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.2873
CCL2 chemokine (C-C motif) ligand 2 3.24841
PPARG peroxisome proliferator-activated receptor gamma 3.16153
LSR lipolysis stimulated lipoprotein receptor 2.99742
CIAO3 cytosolic iron-sulfur assembly component 3 2.95979
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.63855
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.57158
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.37973
VGLL4 vestigial-like family member 4 2.34891
BAX BCL2-associated X protein 2.22095
KDM5A lysine (K)-specific demethylase 5A 2.10538
HSPA1A heat shock 70kDa protein 1A 2.05829
TRIM16 tripartite motif containing 16 2.04201
DPP4 dipeptidyl-peptidase 4 2.03962
TEX10 testis expressed 10 2.00675
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.00157

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -6.16567
TLR4 toll-like receptor 4 -5.57029
INPP1 inositol polyphosphate-1-phosphatase -4.15895
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.83979
PCCB propionyl CoA carboxylase, beta polypeptide -3.52819
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.50462
DNM1L dynamin 1-like -3.42518
TOMM34 translocase of outer mitochondrial membrane 34 -3.25916
OXA1L oxidase (cytochrome c) assembly 1-like -3.18423
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.01415
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.93146
PSRC1 proline/serine-rich coiled-coil 1 -2.92604
VAT1 vesicle amine transport 1 -2.89815
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.71509
GNAS GNAS complex locus -2.62112
LYPLA1 lysophospholipase I -2.5303
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.51982
LAP3 leucine aminopeptidase 3 -2.44529
LAGE3 L antigen family, member 3 -2.34535
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -2.29778
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.2312
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.21311
EGF epidermal growth factor -2.15205
ZMIZ1 zinc finger, MIZ-type containing 1 -2.14248
CCNB2 cyclin B2 -2.11782
MPC2 mitochondrial pyruvate carrier 2 -2.0543
SNX11 sorting nexin 11 -2.0446