CRCGN009_HEPG2_24H:A11 Gene Set
Genes
52 genes differentially expressed following the CRCGN009_HEPG2_24H:A11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
6.99302
|
|
RPL39L
|
ribosomal protein L39-like
|
6.53794
|
|
GPATCH8
|
G patch domain containing 8
|
5.33114
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
5.22127
|
|
CYCS
|
cytochrome c, somatic
|
4.91893
|
|
MAP7
|
microtubule-associated protein 7
|
4.76191
|
|
CHN1
|
chimerin 1
|
4.17632
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.56036
|
|
STK10
|
serine/threonine kinase 10
|
3.52391
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.2873
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.24841
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.16153
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.99742
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.95979
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.63855
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.57158
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.37973
|
|
VGLL4
|
vestigial-like family member 4
|
2.34891
|
|
BAX
|
BCL2-associated X protein
|
2.22095
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.10538
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.05829
|
|
TRIM16
|
tripartite motif containing 16
|
2.04201
|
|
DPP4
|
dipeptidyl-peptidase 4
|
2.03962
|
|
TEX10
|
testis expressed 10
|
2.00675
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.00157
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.16567
|
|
TLR4
|
toll-like receptor 4
|
-5.57029
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
-4.15895
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.83979
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.52819
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.50462
|
|
DNM1L
|
dynamin 1-like
|
-3.42518
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-3.25916
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.18423
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.01415
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.93146
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.92604
|
|
VAT1
|
vesicle amine transport 1
|
-2.89815
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.71509
|
|
GNAS
|
GNAS complex locus
|
-2.62112
|
|
LYPLA1
|
lysophospholipase I
|
-2.5303
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
-2.51982
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.44529
|
|
LAGE3
|
L antigen family, member 3
|
-2.34535
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.29778
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.2312
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.21311
|
|
EGF
|
epidermal growth factor
|
-2.15205
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.14248
|
|
CCNB2
|
cyclin B2
|
-2.11782
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
-2.0543
|
|
SNX11
|
sorting nexin 11
|
-2.0446
|