| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | propyl gallate 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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86 genes differentially expressed following the CRCGN009_HEPG2_24H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 5.2085 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 5.048 |
| PRR15L | proline rich 15-like | 4.79386 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.17647 |
| CHN1 | chimerin 1 | 4.16388 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.13651 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.1279 |
| CYCS | cytochrome c, somatic | 3.94952 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.84815 |
| KIFBP | kinesin family binding protein | 3.6604 |
| STIMATE | STIM activating enhancer | 3.5255 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.52481 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.48894 |
| MYLK | myosin light chain kinase | 3.47533 |
| FCHO1 | FCH domain only 1 | 3.24674 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.21651 |
| INTS3 | integrator complex subunit 3 | 3.14006 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.10429 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 3.02745 |
| FZD7 | frizzled class receptor 7 | 2.82201 |
| CCDC85B | coiled-coil domain containing 85B | 2.80994 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.74943 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.73872 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.72176 |
| GHR | growth hormone receptor | 2.6928 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.68311 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.67724 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.61685 |
| KLHL21 | kelch-like family member 21 | 2.58682 |
| STK10 | serine/threonine kinase 10 | 2.53139 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase | 2.43294 |
| LOXL1 | lysyl oxidase-like 1 | 2.30154 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.29373 |
| TGFB3 | transforming growth factor, beta 3 | 2.25483 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.25074 |
| FUT2 | fucosyltransferase 2 (secretor status included) | 2.22548 |
| ANKRD40 | ankyrin repeat domain 40 | 2.12911 |
| DUSP4 | dual specificity phosphatase 4 | 2.11668 |
| HDGFL3 | HDGF like 3 | 2.10654 |
| CHEK2 | checkpoint kinase 2 | 2.10183 |
| DIPK1A | divergent protein kinase domain 1A | 2.07184 |
| TBP | TATA box binding protein | 2.00196 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | -7.52014 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.38434 |
| ADI1 | acireductone dioxygenase 1 | -6.1632 |
| FAIM | Fas apoptotic inhibitory molecule | -3.71973 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.64735 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.5233 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.42881 |
| NGRN | neugrin, neurite outgrowth associated | -3.35959 |
| GNAS | GNAS complex locus | -3.24396 |
| LAP3 | leucine aminopeptidase 3 | -3.03207 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -2.99866 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.89359 |
| ZNF586 | zinc finger protein 586 | -2.84566 |
| RAI14 | retinoic acid induced 14 | -2.79297 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.74357 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.59992 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.56716 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -2.52725 |
| EGF | epidermal growth factor | -2.4596 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | -2.35315 |
| CAB39 | calcium binding protein 39 | -2.32635 |
| KIF13A | kinesin family member 13A | -2.32423 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.28898 |
| ZFP37 | ZFP37 zinc finger protein | -2.28765 |
| MYCT1 | myc target 1 | -2.28087 |
| SLC35F2 | solute carrier family 35, member F2 | -2.27838 |
| GOLT1B | golgi transport 1B | -2.27568 |
| ENTREP2 | endosomal transmembrane epsin interactor 2 | -2.27496 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -2.26421 |
| GRB10 | growth factor receptor-bound protein 10 | -2.2347 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | -2.21433 |
| PLPPR1 | phospholipid phosphatase related 1 | -2.18128 |
| ELAC1 | elaC ribonuclease Z 1 | -2.17613 |
| ANKRD10 | ankyrin repeat domain 10 | -2.15898 |
| SH3GL1 | SH3-domain GRB2-like 1 | -2.12478 |
| LOC102724560 | cystathionine beta-synthase | -2.10489 |
| SUSD5 | sushi domain containing 5 | -2.08574 |
| GLRA1 | glycine receptor, alpha 1 | -2.0568 |
| PIH1D1 | PIH1 domain containing 1 | -2.05374 |
| TLCD3A | TLC domain containing 3A | -2.01865 |
| ANO10 | anoctamin 10 | -2.01311 |
| TOR1A | torsin family 1, member A (torsin A) | -2.00851 |
| NOX4 | NADPH oxidase 4 | -2.00636 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -2.00421 |