CRCGN009_HEPG2_24H:A16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-aminoazotoluene 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

465 genes differentially expressed following the CRCGN009_HEPG2_24H:A16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 8.12765
INPP1 inositol polyphosphate-1-phosphatase 7.99161
BLCAP bladder cancer associated protein 6.96473
ABHD4 abhydrolase domain containing 4 6.70476
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 6.4159
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 6.2728
MICALL1 MICAL-like 1 6.24042
DDB2 damage-specific DNA binding protein 2, 48kDa 5.90841
KIFBP kinesin family binding protein 5.87474
CEMIP2 cell migration inducing hyaluronidase 2 5.4066
MYLK myosin light chain kinase 5.36721
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 5.33484
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 5.20039
TIMP2 TIMP metallopeptidase inhibitor 2 5.06435
FOSL1 FOS-like antigen 1 4.50019
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.37432
ANKRD10 ankyrin repeat domain 10 4.36989
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.33772
MAP7 microtubule-associated protein 7 4.31554
GPC1 glypican 1 4.2578
CCDC92 coiled-coil domain containing 92 4.15518
LRP10 low density lipoprotein receptor-related protein 10 4.15208
KEAP1 kelch-like ECH-associated protein 1 4.13738
CASC3 cancer susceptibility candidate 3 4.12441
KDM5A lysine (K)-specific demethylase 5A 4.12284
TXNRD1 thioredoxin reductase 1 4.11722
TEX10 testis expressed 10 4.07568
LCN2 lipocalin 2 4.07357
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.98696
CNPY3 canopy FGF signaling regulator 3 3.75064
RPP38 ribonuclease P/MRP 38kDa subunit 3.68935
BAX BCL2-associated X protein 3.67749
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 3.67043
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.66601
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.64811
E2F2 E2F transcription factor 2 3.53907
CCNF cyclin F 3.53653
DUSP14 dual specificity phosphatase 14 3.53454
XPC xeroderma pigmentosum, complementation group C 3.50826
TUBB6 tubulin, beta 6 class V 3.50592
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.49509
RAP1GAP RAP1 GTPase activating protein 3.46807
MAP7D1 MAP7 domain containing 1 3.40083
TERF2IP telomeric repeat binding factor 2, interacting protein 3.2856
SESN1 sestrin 1 3.28457
PROSER1 proline and serine rich 1 3.26925
PPIE peptidylprolyl isomerase E (cyclophilin E) 3.25742
PRKCD protein kinase C, delta 3.25522
PLK3 polo-like kinase 3 3.18821
MOK MOK protein kinase 3.16657
VAT1 vesicle amine transport 1 3.15709
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 3.15319
CARMIL1 capping protein regulator and myosin 1 linker 1 3.14577
PRAF2 PRA1 domain family, member 2 3.11116
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 3.10137
GADD45A growth arrest and DNA-damage-inducible, alpha 3.0774
PPARG peroxisome proliferator-activated receptor gamma 3.05574
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.03193
TIGAR TP53 induced glycolysis regulatory phosphatase 2.98269
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.97863
RALGDS ral guanine nucleotide dissociation stimulator 2.95998
RPL39L ribosomal protein L39-like 2.9597
ADGRG1 adhesion G protein-coupled receptor G1 2.93118
LPAR2 lysophosphatidic acid receptor 2 2.92602
ZMYM2 zinc finger, MYM-type 2 2.92418
SKIC2 SKI2 subunit of superkiller complex 2.89801
RBM15B RNA binding motif protein 15B 2.87025
UBE2A ubiquitin-conjugating enzyme E2A 2.86159
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.84799
DUSP6 dual specificity phosphatase 6 2.84203
TOR1A torsin family 1, member A (torsin A) 2.8191
TRAM2 translocation associated membrane protein 2 2.80217
ADNP activity-dependent neuroprotector homeobox 2.78307
NISCH nischarin 2.77805
GSTZ1 glutathione S-transferase zeta 1 2.76631
ZNF282 zinc finger protein 282 2.74804
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.73893
BACE2 beta-site APP-cleaving enzyme 2 2.71327
ADRB2 adrenoceptor beta 2, surface 2.70308
ZMAT3 zinc finger, matrin-type 3 2.68949
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.6845
ADGRE5 adhesion G protein-coupled receptor E5 2.68013
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.66761
GATA3 GATA binding protein 3 2.64979
TICAM1 toll-like receptor adaptor molecule 1 2.62295
STXBP1 syntaxin binding protein 1 2.61038
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 2.60709
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.59672
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.58985
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.55756
CCP110 centriolar coiled coil protein 110kDa 2.51333
IL4R interleukin 4 receptor 2.50689
LSR lipolysis stimulated lipoprotein receptor 2.49908
HDGFL3 HDGF like 3 2.48212
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 2.44738
NUP58 nucleoporin 58 2.43698
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.4364
GABARAPL1 GABA(A) receptor-associated protein like 1 2.42842
ATG9A autophagy related 9A 2.41388
UBE3C ubiquitin protein ligase E3C 2.40744
LSG1 large 60S subunit nuclear export GTPase 1 2.39836
CDR2L cerebellar degeneration-related protein 2-like 2.39364
ACTA2 actin, alpha 2, smooth muscle, aorta 2.39346
CCDC86 coiled-coil domain containing 86 2.37
LRRC41 leucine rich repeat containing 41 2.36956
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.35404
ZFP36 ZFP36 ring finger protein 2.33201
TRIM32 tripartite motif containing 32 2.32435
FNBP4 formin binding protein 4 2.32257
SLC75A1 solute carrier family 75 member 1 2.32033
THSD1 thrombospondin, type I, domain containing 1 2.31301
ZNF79 zinc finger protein 79 2.31281
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.31101
PRRC2B proline-rich coiled-coil 2B 2.29914
SMAD3 SMAD family member 3 2.2834
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.27261
STOM stomatin 2.25501
GAPVD1 GTPase activating protein and VPS9 domains 1 2.25398
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.2368
SETD1A SET domain containing 1A 2.23314
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 2.23306
IGFBP3 insulin-like growth factor binding protein 3 2.22829
ZDHHC11B zinc finger, DHHC-type containing 11B 2.21983
FOXJ3 forkhead box J3 2.20592
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.20423
TIAM1 T-cell lymphoma invasion and metastasis 1 2.20224
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.19985
TSC22D3 TSC22 domain family, member 3 2.19004
ULK1 unc-51 like autophagy activating kinase 1 2.18521
ATF3 activating transcription factor 3 2.18417
UBQLN2 ubiquilin 2 2.18081
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.17438
BAG3 BCL2-associated athanogene 3 2.1739
KLHL21 kelch-like family member 21 2.16327
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.16075
HDAC7 histone deacetylase 7 2.14427
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.13099
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.11903
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.11416
DGKD diacylglycerol kinase, delta 130kDa 2.11276
DOLK dolichol kinase 2.10945
STX1A syntaxin 1A (brain) 2.1082
CCL2 chemokine (C-C motif) ligand 2 2.10522
TSC1 tuberous sclerosis 1 2.10152
TRAPPC14 trafficking protein particle complex subunit 14 2.09556
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.09173
ZNF536 zinc finger protein 536 2.09171
CPT1B carnitine palmitoyltransferase 1B (muscle) 2.08581
GIPC1 GIPC PDZ domain containing family, member 1 2.07664
DDIT4 DNA-damage-inducible transcript 4 2.06789
LOC122526780 uncharacterized LOC122526780 2.06637
FRS2 fibroblast growth factor receptor substrate 2 2.06133
TBC1D10C TBC1 domain family, member 10C 2.04827
FPGS folylpolyglutamate synthase 2.04821
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.04542
FXYD5 FXYD domain containing ion transport regulator 5 2.04527
GPATCH8 G patch domain containing 8 2.03971
PROCR protein C receptor, endothelial 2.03345
BRD1 bromodomain containing 1 2.03178
ATG2A autophagy related 2A 2.03122
NCOA6 nuclear receptor coactivator 6 2.02529
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.02041
DNM1L dynamin 1-like 2.01872
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 2.0184
DOHH deoxyhypusine hydroxylase/monooxygenase 2.01461
SRPX sushi-repeat containing protein, X-linked 2.01286
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.01271
SQOR sulfide quinone oxidoreductase 2.00915
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.00822
FASN fatty acid synthase 2.0071
ASCC3 activating signal cointegrator 1 complex subunit 3 2.00117
CPEB1 cytoplasmic polyadenylation element binding protein 1 2.00053
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 2.00016

decreased expression

Symbol Name Standardized Value
ISOC1 isochorismatase domain containing 1 -8.22993
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -7.90583
LOC124907782 dual specificity protein phosphatase 22 -7.17373
ALDOC aldolase C, fructose-bisphosphate -6.74072
PECR peroxisomal trans-2-enoyl-CoA reductase -6.71884
FGFR4 fibroblast growth factor receptor 4 -6.62951
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -6.62242
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -6.44896
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -6.07149
TCTN1 tectonic family member 1 -5.91258
SOAT2 sterol O-acyltransferase 2 -5.89542
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -5.78276
TLR4 toll-like receptor 4 -5.67384
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.47679
HAT1 histone acetyltransferase 1 -5.31116
RSU1 Ras suppressor protein 1 -5.27017
ZW10 zw10 kinetochore protein -5.2642
CDC20 cell division cycle 20 -5.04285
MSRA methionine sulfoxide reductase A -4.90208
HYOU1 hypoxia up-regulated 1 -4.8535
MYL9 myosin, light chain 9, regulatory -4.80027
MNAT1 MNAT CDK-activating kinase assembly factor 1 -4.76067
ANO10 anoctamin 10 -4.74129
NUCB2 nucleobindin 2 -4.52879
PCCB propionyl CoA carboxylase, beta polypeptide -4.51621
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.40956
PSRC1 proline/serine-rich coiled-coil 1 -4.35115
DERA deoxyribose-phosphate aldolase (putative) -4.28035
COG2 component of oligomeric golgi complex 2 -4.25679
PGM1 phosphoglucomutase 1 -4.15149
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.10647
PROS1 protein S (alpha) -4.07841
AMDHD2 amidohydrolase domain containing 2 -4.03684
A1CF APOBEC1 complementation factor -3.98997
ACAA1 acetyl-CoA acyltransferase 1 -3.86108
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.74199
CCNB1 cyclin B1 -3.70846
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -3.70286
RPIA ribose 5-phosphate isomerase A -3.64349
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.62648
BLMH bleomycin hydrolase -3.56792
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -3.52431
HPR haptoglobin-related protein -3.51581
APOC3 apolipoprotein C-III -3.51501
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -3.4784
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.45222
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.39247
PLG plasminogen -3.38672
RFC2 replication factor C (activator 1) 2, 40kDa -3.38652
HADH hydroxyacyl-CoA dehydrogenase -3.35988
PEG10 paternally expressed 10 -3.35279
CFHR2 complement factor H-related 2 -3.34275
LBR lamin B receptor -3.33693
PHKB phosphorylase kinase, beta -3.3319
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.29132
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.28719
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.22406
ICAM3 intercellular adhesion molecule 3 -3.21859
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -3.20695
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.15396
ADH6 alcohol dehydrogenase 6 (class V) -3.15256
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.14921
PLS1 plastin 1 -3.13982
AURKB aurora kinase B -3.13822
CRELD2 cysteine-rich with EGF-like domains 2 -3.13612
SLC30A10 solute carrier family 30, member 10 -3.11949
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.08304
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.05299
FABP1 fatty acid binding protein 1, liver -3.05292
CPB2 carboxypeptidase B2 (plasma) -3.05127
PLK1 polo-like kinase 1 -3.04635
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.00882
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.99966
MBL2 mannose-binding lectin (protein C) 2, soluble -2.95614
HPX hemopexin -2.94311
HMGA2 high mobility group AT-hook 2 -2.93474
PAH phenylalanine hydroxylase -2.92992
APOM apolipoprotein M -2.85865
LIPC lipase, hepatic -2.85834
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.83587
AMBP alpha-1-microglobulin/bikunin precursor -2.83366
SDF2L1 stromal cell-derived factor 2-like 1 -2.8299
C8G complement component 8, gamma polypeptide -2.82246
ECEL1 endothelin converting enzyme-like 1 -2.82123
VTN vitronectin -2.81163
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.80618
AKR1C4 aldo-keto reductase family 1, member C4 -2.79878
SLC17A2 solute carrier family 17, member 2 -2.78522
ASGR1 asialoglycoprotein receptor 1 -2.77328
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.7704
UPB1 ureidopropionase, beta -2.76757
HPCA hippocalcin -2.7655
NGRN neugrin, neurite outgrowth associated -2.75338
TTPA tocopherol (alpha) transfer protein -2.74912
GIPC2 GIPC PDZ domain containing family, member 2 -2.7488
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -2.73414
FCHSD2 FCH and double SH3 domains 2 -2.72826
ANXA7 annexin A7 -2.72487
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.72009
ANO3 anoctamin 3 -2.71933
DENND2D DENN/MADD domain containing 2D -2.70943
CCNA2 cyclin A2 -2.70271
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -2.69482
APOA1 apolipoprotein A-I -2.67812
APCS amyloid P component, serum -2.67685
FOS FBJ murine osteosarcoma viral oncogene homolog -2.66163
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.66162
ARID5B AT rich interactive domain 5B (MRF1-like) -2.66069
C5 complement component 5 -2.66058
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.65004
ELP4 elongator acetyltransferase complex subunit 4 -2.64931
AHSG alpha-2-HS-glycoprotein -2.63825
PKLR pyruvate kinase, liver and RBC -2.63491
AMT aminomethyltransferase -2.63152
MVD mevalonate (diphospho) decarboxylase -2.62779
ACSM2A acyl-CoA synthetase medium-chain family member 2A -2.62352
MSMO1 methylsterol monooxygenase 1 -2.62214
PGAM4 phosphoglycerate mutase family member 4 -2.61878
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.61729
F13B coagulation factor XIII, B polypeptide -2.617
HEBP1 heme binding protein 1 -2.60605
MRPL12 mitochondrial ribosomal protein L12 -2.60592
GALK1 galactokinase 1 -2.60367
APOH apolipoprotein H (beta-2-glycoprotein I) -2.5898
STMN1 stathmin 1 -2.57779
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.56964
CRIPTO3 cripto, EGF-CFC family member 3 -2.56935
FAM117A family with sequence similarity 117, member A -2.56556
TRAPPC3 trafficking protein particle complex 3 -2.56025
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.55242
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.54342
MSH6 mutS homolog 6 -2.53871
FBF1 Fas (TNFRSF6) binding factor 1 -2.53814
APOA2 apolipoprotein A-II -2.5373
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.52986
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.52558
MAT1A methionine adenosyltransferase I, alpha -2.52347
ECH1 enoyl CoA hydratase 1, peroxisomal -2.5227
MYRIP myosin VIIA and Rab interacting protein -2.51915
NR1I3 nuclear receptor subfamily 1, group I, member 3 -2.51649
NOD2 nucleotide-binding oligomerization domain containing 2 -2.50164
STAP2 signal transducing adaptor family member 2 -2.49794
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.49719
ORM2 orosomucoid 2 -2.49642
FGA fibrinogen alpha chain -2.49587
G6PC1 glucose-6-phosphatase catalytic subunit 1 -2.48967
MANF mesencephalic astrocyte-derived neurotrophic factor -2.48902
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -2.48819
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -2.48443
ENO1 enolase 1, (alpha) -2.48364
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.48135
RRAGB Ras-related GTP binding B -2.47159
SAA4 serum amyloid A4, constitutive -2.46603
ATRNL1 attractin-like 1 -2.46469
CFHR5 complement factor H-related 5 -2.4596
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.45865
ALPL alkaline phosphatase, liver/bone/kidney -2.45704
SERP1 stress-associated endoplasmic reticulum protein 1 -2.45264
MAGOHB mago-nashi homolog B (Drosophila) -2.45246
ADI1 acireductone dioxygenase 1 -2.44589
KHK ketohexokinase (fructokinase) -2.43656
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.42581
MPC1 mitochondrial pyruvate carrier 1 -2.42461
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -2.42415
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -2.41403
GTF2A2 general transcription factor IIA, 2, 12kDa -2.41335
LIME1 Lck interacting transmembrane adaptor 1 -2.41024
RPS5 ribosomal protein S5 -2.40508
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.40417
ANG angiogenin, ribonuclease, RNase A family, 5 -2.39781
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.38961
PID1 phosphotyrosine interaction domain containing 1 -2.38577
TKFC triokinase/FMN cyclase -2.36889
GLYAT glycine-N-acyltransferase -2.36031
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.35507
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -2.35484
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -2.35326
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -2.35121
GPC5 glypican 5 -2.3496
MRPL23 mitochondrial ribosomal protein L23 -2.34391
CPNE2 copine II -2.33793
SEH1L SEH1-like (S. cerevisiae) -2.33241
SCAMP5 secretory carrier membrane protein 5 -2.32595
APOB apolipoprotein B -2.32567
OCEL1 occludin/ELL domain containing 1 -2.32479
MTTP microsomal triglyceride transfer protein -2.30963
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 -2.30898
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 -2.30738
TM9SF3 transmembrane 9 superfamily member 3 -2.30668
GPR88 G protein-coupled receptor 88 -2.30507
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.30371
ACADSB acyl-CoA dehydrogenase, short/branched chain -2.30146
TMEM176A transmembrane protein 176A -2.29221
DPYS dihydropyrimidinase -2.28981
ASGR2 asialoglycoprotein receptor 2 -2.28879
RUNDC3B RUN domain containing 3B -2.28002
PDZD2 PDZ domain containing 2 -2.27923
ETAA1 Ewing tumor-associated antigen 1 -2.27612
SATB1 SATB homeobox 1 -2.27056
KIF14 kinesin family member 14 -2.26527
F9 coagulation factor IX -2.26307
CNN3 calponin 3, acidic -2.2581
INHA inhibin, alpha -2.25536
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -2.25463
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.25087
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.24783
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 -2.24772
CSK c-src tyrosine kinase -2.22163
ZDHHC6 zinc finger, DHHC-type containing 6 -2.21779
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.21165
CFHR3 complement factor H-related 3 -2.20904
DUT deoxyuridine triphosphatase -2.2055
MSH2 mutS homolog 2 -2.20545
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.19882
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.19102
GOLPH3L golgi phosphoprotein 3-like -2.18779
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -2.18652
PXMP2 peroxisomal membrane protein 2, 22kDa -2.18453
HDAC2 histone deacetylase 2 -2.1822
CCL15 chemokine (C-C motif) ligand 15 -2.18194
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.17795
ANGPTL3 angiopoietin-like 3 -2.167
CZIB CXXC motif containing zinc binding protein -2.16143
CA5A carbonic anhydrase VA, mitochondrial -2.16106
EMC9 ER membrane protein complex subunit 9 -2.16041
TTC27 tetratricopeptide repeat domain 27 -2.1581
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.15513
TTF2 transcription termination factor, RNA polymerase II -2.14611
PRDM12 PR domain containing 12 -2.14484
GPR6 G protein-coupled receptor 6 -2.14237
C8A complement component 8, alpha polypeptide -2.14227
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.13938
CRYZ crystallin, zeta (quinone reductase) -2.13841
TBX10 T-box 10 -2.13384
RGS7 regulator of G-protein signaling 7 -2.12908
TTC1 tetratricopeptide repeat domain 1 -2.12855
KNG1 kininogen 1 -2.12528
ZMAT5 zinc finger, matrin-type 5 -2.12455
MCTP1 multiple C2 domains, transmembrane 1 -2.12153
GC group-specific component (vitamin D binding protein) -2.11212
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -2.10922
XYLB xylulokinase homolog (H. influenzae) -2.10452
FMO5 flavin containing monooxygenase 5 -2.10235
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.09699
NOL11 nucleolar protein 11 -2.09332
HSPE1 heat shock 10kDa protein 1 -2.08854
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -2.08404
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.08304
GALK2 galactokinase 2 -2.08123
PARP1 poly (ADP-ribose) polymerase 1 -2.08122
RNF130 ring finger protein 130 -2.0805
PIH1D1 PIH1 domain containing 1 -2.08022
BABAM1 BRISC and BRCA1 A complex member 1 -2.07495
RAB4B RAB4B, member RAS oncogene family -2.07427
ANKRD46 ankyrin repeat domain 46 -2.07168
CDK4 cyclin-dependent kinase 4 -2.07146
FRMPD1 FERM and PDZ domain containing 1 -2.07021
TCEAL4 transcription elongation factor A (SII)-like 4 -2.06695
CCDC47 coiled-coil domain containing 47 -2.06637
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.06594
LMBR1 limb development membrane protein 1 -2.06541
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.06534
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.06212
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -2.06185
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -2.05525
SNCAIP synuclein, alpha interacting protein -2.05413
INHBE inhibin, beta E -2.05139
PIPOX pipecolic acid oxidase -2.05021
SLC38A4 solute carrier family 38, member 4 -2.0452
JRKL JRK-like -2.04112
ACTL6A actin-like 6A -2.03885
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.03824
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -2.03722
PMVK phosphomevalonate kinase -2.03496
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -2.03469
ARSL arylsulfatase L -2.02691
CGREF1 cell growth regulator with EF-hand domain 1 -2.02686
RNASE4 ribonuclease, RNase A family, 4 -2.02653
GPHN gephyrin -2.0218
COX17 COX17 cytochrome c oxidase copper chaperone -2.02036
RNF2 ring finger protein 2 -2.01964
TIPRL TOR signaling pathway regulator -2.01799
SUSD5 sushi domain containing 5 -2.01566
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.01453
FMO1 flavin containing monooxygenase 1 -2.01294
RPA3 replication protein A3, 14kDa -2.01183
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.0066
CDK1 cyclin-dependent kinase 1 -2.00348
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.00272
NECAB2 N-terminal EF-hand calcium binding protein 2 -2.00064
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.00053