CRCGN009_HEPG2_24H:A19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyl parathion 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN009_HEPG2_24H:A19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.86209
JADE2 jade family PHD finger 2 4.49796
CDPF1 cysteine-rich, DPF motif domain containing 1 3.70865
TIAM1 T-cell lymphoma invasion and metastasis 1 3.66217
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.6487
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 3.36745
KLHL9 kelch-like family member 9 3.25933
PPARG peroxisome proliferator-activated receptor gamma 3.01205
RPP38 ribonuclease P/MRP 38kDa subunit 2.78244
LOC122526780 uncharacterized LOC122526780 2.76113
PMM2 phosphomannomutase 2 2.53841
CEP57 centrosomal protein 57kDa 2.51241
DNM1 dynamin 1 2.45051
GPATCH8 G patch domain containing 8 2.42751
FOXJ3 forkhead box J3 2.27448

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -8.1592
DHRS7 dehydrogenase/reductase (SDR family) member 7 -5.16303
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.88767
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.54525
ZMIZ1 zinc finger, MIZ-type containing 1 -4.49094
CCNB2 cyclin B2 -4.18177
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.12251
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.71522
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.56489
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.43075
TWF2 twinfilin actin binding protein 2 -3.3134
RNF167 ring finger protein 167 -2.80445
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.65823
FBXL12 F-box and leucine-rich repeat protein 12 -2.63372
GNAS GNAS complex locus -2.42849
RFC2 replication factor C (activator 1) 2, 40kDa -2.38907
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.35523
ADI1 acireductone dioxygenase 1 -2.33124
MAPK13 mitogen-activated protein kinase 13 -2.21171
PLA2G15 phospholipase A2, group XV -2.05008
HLA-DMA major histocompatibility complex, class II, DM alpha -2.03871
ZW10 zw10 kinetochore protein -2.01589