CRCGN009_HEPG2_24H:A20 Gene Set
Genes
59 genes differentially expressed following the CRCGN009_HEPG2_24H:A20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CBR3
|
carbonyl reductase 3
|
7.01871
|
|
JADE2
|
jade family PHD finger 2
|
5.62808
|
|
LCN2
|
lipocalin 2
|
4.75655
|
|
PRR15L
|
proline rich 15-like
|
3.72999
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.60551
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
3.43939
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.42161
|
|
NOTCH1
|
notch 1
|
3.35536
|
|
RPL39L
|
ribosomal protein L39-like
|
3.24179
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.23219
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.13366
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.96073
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.95748
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.95018
|
|
EPHB2
|
EPH receptor B2
|
2.93604
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.90225
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.85494
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.8341
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.73235
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.67668
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.61804
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.57019
|
|
FZD7
|
frizzled class receptor 7
|
2.54837
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.53376
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.45215
|
|
MAP7
|
microtubule-associated protein 7
|
2.40004
|
|
CHN1
|
chimerin 1
|
2.36576
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.2469
|
|
CDC45
|
cell division cycle 45
|
2.23304
|
|
TBP
|
TATA box binding protein
|
2.19257
|
|
ADM2
|
adrenomedullin 2
|
2.14396
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-5.07899
|
|
CCNB2
|
cyclin B2
|
-4.74899
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.25857
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.64918
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.6483
|
|
CAB39
|
calcium binding protein 39
|
-3.52689
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.32362
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.26334
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.22687
|
|
GDF15
|
growth differentiation factor 15
|
-3.05311
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.91815
|
|
LDHD
|
lactate dehydrogenase D
|
-2.87931
|
|
VAT1
|
vesicle amine transport 1
|
-2.80538
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.78015
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.64774
|
|
GNAS
|
GNAS complex locus
|
-2.54238
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.53692
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.40503
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.28428
|
|
SESN1
|
sestrin 1
|
-2.27686
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.26007
|
|
MTFR1
|
mitochondrial fission regulator 1
|
-2.24293
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.20435
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.18152
|
|
DHRS3
|
dehydrogenase/reductase (SDR family) member 3
|
-2.17835
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.15846
|
|
CDC25B
|
cell division cycle 25B
|
-2.12381
|
|
CCNB1
|
cyclin B1
|
-2.09701
|
