CRCGN009_HEPG2_24H:A21 Gene Set
Genes
46 genes differentially expressed following the CRCGN009_HEPG2_24H:A21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
10.0
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.22326
|
|
EAPP
|
E2F-associated phosphoprotein
|
5.34868
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.42521
|
|
MYLK
|
myosin light chain kinase
|
4.14204
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.92713
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.89637
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
3.65942
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.57914
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.53476
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.35311
|
|
RPL39L
|
ribosomal protein L39-like
|
3.30482
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.24594
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.87592
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.6627
|
|
GPATCH8
|
G patch domain containing 8
|
2.30616
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
2.30041
|
|
GATA3
|
GATA binding protein 3
|
2.28723
|
|
IDE
|
insulin-degrading enzyme
|
2.28591
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.20863
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.17033
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.1252
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.09871
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.75312
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-7.68269
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-6.37516
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.08097
|
|
GNAS
|
GNAS complex locus
|
-4.5077
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-4.2526
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.95112
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.85915
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.60424
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.53108
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.27668
|
|
HMG20B
|
high mobility group 20B
|
-2.86903
|
|
CCNB1
|
cyclin B1
|
-2.61646
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.60657
|
|
GRB7
|
growth factor receptor-bound protein 7
|
-2.44392
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.44207
|
|
TMEM115
|
transmembrane protein 115
|
-2.38947
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.34831
|
|
PDE6A
|
phosphodiesterase 6A, cGMP-specific, rod, alpha
|
-2.31246
|
|
EGF
|
epidermal growth factor
|
-2.28526
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.06998
|
|
ACTR8
|
ARP8 actin-related protein 8 homolog (yeast)
|
-2.05653
|
|
STAP1
|
signal transducing adaptor family member 1
|
-2.01734
|
