CRCGN009_HEPG2_24H:A22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyl parathion 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN009_HEPG2_24H:A22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCL2 chemokine (C-C motif) ligand 2 6.26764
SNAP25 synaptosomal-associated protein, 25kDa 5.23726
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.60185
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.12342
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.86224
EPN2 epsin 2 3.76412
SOCS2 suppressor of cytokine signaling 2 3.65657
GPER1 G protein-coupled estrogen receptor 1 3.25784
PEX11A peroxisomal biogenesis factor 11 alpha 3.12164
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.9472
STIMATE STIM activating enhancer 2.89251
LPAR2 lysophosphatidic acid receptor 2 2.84891
CEP57 centrosomal protein 57kDa 2.79873
MAP7 microtubule-associated protein 7 2.77855
CYCS cytochrome c, somatic 2.76781
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.75535
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.68613
PFKL phosphofructokinase, liver 2.48578
EGF epidermal growth factor 2.27277
FOXJ3 forkhead box J3 2.26731
HLA-DMA major histocompatibility complex, class II, DM alpha 2.25214
GPATCH8 G patch domain containing 8 2.16434
SNX7 sorting nexin 7 2.07416
FAM168B family with sequence similarity 168, member B 2.03592
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.02116
WSCD1 WSC domain containing 1 2.01359

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.38598
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -5.38483
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -5.30478
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.97748
PECR peroxisomal trans-2-enoyl-CoA reductase -4.53377
CCNB2 cyclin B2 -4.25019
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.89157
TWF2 twinfilin actin binding protein 2 -3.21121
MAPK13 mitogen-activated protein kinase 13 -3.122
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.6843
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.27639
DSG3 desmoglein 3 -2.07176
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.04946