CRCGN009_HEPG2_24H:A23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyl parathion 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

47 genes differentially expressed following the CRCGN009_HEPG2_24H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STIMATE STIM activating enhancer 5.94729
STK10 serine/threonine kinase 10 4.69877
ALDOC aldolase C, fructose-bisphosphate 4.43508
GPER1 G protein-coupled estrogen receptor 1 4.03605
CARMIL1 capping protein regulator and myosin 1 linker 1 3.80646
LCN2 lipocalin 2 3.66761
CCL2 chemokine (C-C motif) ligand 2 3.65586
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.56955
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.225
SQOR sulfide quinone oxidoreductase 2.959
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.92698
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.9175
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.82091
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.81419
PPARG peroxisome proliferator-activated receptor gamma 2.79375
DYNLT3 dynein, light chain, Tctex-type 3 2.72348
LOC122526780 uncharacterized LOC122526780 2.67788
CYCS cytochrome c, somatic 2.60056
UBQLN2 ubiquilin 2 2.57793
MAP7 microtubule-associated protein 7 2.52213
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.44387
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.44327
PRR15L proline rich 15-like 2.38056
FOXJ3 forkhead box J3 2.34201
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.19994
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.15651

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -10.0
NGRN neugrin, neurite outgrowth associated -5.90784
TLR4 toll-like receptor 4 -5.53732
PRPF4 pre-mRNA processing factor 4 -4.11433
OXA1L oxidase (cytochrome c) assembly 1-like -4.0107
TWF2 twinfilin actin binding protein 2 -3.68875
PCNA proliferating cell nuclear antigen -3.5921
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.33047
VDAC1 voltage-dependent anion channel 1 -3.32821
MAPK13 mitogen-activated protein kinase 13 -3.10355
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.72541
TOR1A torsin family 1, member A (torsin A) -2.68775
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.66301
DDIT4 DNA-damage-inducible transcript 4 -2.58661
FBXO7 F-box protein 7 -2.53057
EIF5 eukaryotic translation initiation factor 5 -2.37962
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.27509
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.14144
CCNH cyclin H -2.13378
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.07952
EGF epidermal growth factor -2.05206