| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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51 genes differentially expressed following the CRCGN009_HEPG2_24H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.61168 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 7.27515 |
| MAP7 | microtubule-associated protein 7 | 5.46939 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 5.39822 |
| ATP11B | ATPase, class VI, type 11B | 5.15087 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.09054 |
| CYCS | cytochrome c, somatic | 5.05576 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.84239 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.83392 |
| NOTCH1 | notch 1 | 4.56805 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.99494 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.6625 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.54426 |
| ZNF589 | zinc finger protein 589 | 3.37554 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 3.34126 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.22723 |
| STK10 | serine/threonine kinase 10 | 3.0454 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.0293 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 2.90532 |
| PMM2 | phosphomannomutase 2 | 2.54354 |
| KIF20A | kinesin family member 20A | 2.52373 |
| MYLK | myosin light chain kinase | 2.48948 |
| HOXA10 | homeobox A10 | 2.32734 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.27233 |
| SMIM40 | small integral membrane protein 40 | 2.26482 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 2.12264 |
| HEBP1 | heme binding protein 1 | 2.10896 |
| DIPK1A | divergent protein kinase domain 1A | 2.08547 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -5.54322 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.85532 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -4.65996 |
| TLR4 | toll-like receptor 4 | -4.54382 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.4559 |
| CSK | c-src tyrosine kinase | -3.81165 |
| GNAS | GNAS complex locus | -3.80047 |
| NGRN | neugrin, neurite outgrowth associated | -3.69266 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.65437 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.25724 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -3.17009 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -2.96945 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.96677 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.81699 |
| FHL2 | four and a half LIM domains 2 | -2.49621 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.46416 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.24019 |
| LDHD | lactate dehydrogenase D | -2.22932 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.18503 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.15247 |
| SCAMP2 | secretory carrier membrane protein 2 | -2.13607 |
| METTL18 | methyltransferase like 18 | -2.08107 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.06738 |
