CRCGN009_HEPG2_24H:B06 Gene Set
Genes
42 genes differentially expressed following the CRCGN009_HEPG2_24H:B06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.19976
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.42476
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.74454
|
|
CHEK2
|
checkpoint kinase 2
|
3.71386
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.60348
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.55587
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.28336
|
|
LAGE3
|
L antigen family, member 3
|
3.25824
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
3.15582
|
|
PRR15L
|
proline rich 15-like
|
2.81586
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.70637
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.70354
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.6007
|
|
SFTPB
|
surfactant protein B
|
2.51705
|
|
CYCS
|
cytochrome c, somatic
|
2.186
|
|
NOTCH1
|
notch 1
|
2.18568
|
|
CCNF
|
cyclin F
|
2.14352
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.02588
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.00363
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.42897
|
|
CCNB2
|
cyclin B2
|
-4.86969
|
|
TLR4
|
toll-like receptor 4
|
-4.67353
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-4.47498
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-4.24251
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
-4.11994
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.6655
|
|
LDHD
|
lactate dehydrogenase D
|
-3.66548
|
|
CTSD
|
cathepsin D
|
-3.56796
|
|
CD58
|
CD58 molecule
|
-3.45589
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.20463
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.03037
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.71482
|
|
CSK
|
c-src tyrosine kinase
|
-2.69574
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.60051
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.51732
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.42581
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.37458
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.35744
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.21121
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.17326
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.14021
|
|
CDC25B
|
cell division cycle 25B
|
-2.01442
|
