| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | aramite 0.01 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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53 genes differentially expressed following the CRCGN009_HEPG2_24H:B07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 6.63855 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 6.44727 |
| MAP7 | microtubule-associated protein 7 | 4.9317 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.63037 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 4.58066 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.35502 |
| CBR3 | carbonyl reductase 3 | 4.06334 |
| ADRB2 | adrenoceptor beta 2, surface | 3.93673 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 3.9067 |
| KLHL21 | kelch-like family member 21 | 3.72074 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.65403 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.60579 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.5318 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.48683 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.27121 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.11609 |
| ZFP36 | ZFP36 ring finger protein | 2.92499 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.86491 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.66706 |
| DIPK1A | divergent protein kinase domain 1A | 2.66133 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.34596 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.11326 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.0502 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.13838 |
| TLR4 | toll-like receptor 4 | -5.01214 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.95625 |
| UBE3C | ubiquitin protein ligase E3C | -4.76949 |
| CSK | c-src tyrosine kinase | -4.38422 |
| NGRN | neugrin, neurite outgrowth associated | -4.21457 |
| PLK1 | polo-like kinase 1 | -4.19568 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.10393 |
| TSPAN4 | tetraspanin 4 | -4.0487 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.01702 |
| SCAND1 | SCAN domain containing 1 | -3.97319 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.95661 |
| CCNB2 | cyclin B2 | -3.9045 |
| PCNA | proliferating cell nuclear antigen | -3.62275 |
| CDC25B | cell division cycle 25B | -3.46056 |
| ADI1 | acireductone dioxygenase 1 | -3.43095 |
| ZW10 | zw10 kinetochore protein | -3.34521 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -3.00243 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.92871 |
| PLA2G15 | phospholipase A2, group XV | -2.51908 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.47168 |
| DCK | deoxycytidine kinase | -2.23267 |
| SLC35F2 | solute carrier family 35, member F2 | -2.19497 |
| EXT1 | exostosin glycosyltransferase 1 | -2.18681 |
| RNF167 | ring finger protein 167 | -2.17813 |
| TBX2 | T-box 2 | -2.14529 |
| TCTN1 | tectonic family member 1 | -2.1401 |
| REEP5 | receptor accessory protein 5 | -2.10908 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.0922 |
| RPS5 | ribosomal protein S5 | -2.06655 |