CRCGN009_HEPG2_24H:B08 Gene Set
Genes
47 genes differentially expressed following the CRCGN009_HEPG2_24H:B08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.99172
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.82056
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.7475
|
|
EPHB2
|
EPH receptor B2
|
3.55758
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.39146
|
|
UBQLN2
|
ubiquilin 2
|
3.35544
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.20473
|
|
E2F2
|
E2F transcription factor 2
|
3.16949
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.02016
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.95263
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.82972
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.74326
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.72904
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.69359
|
|
FZD7
|
frizzled class receptor 7
|
2.68041
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.67223
|
|
RBKS
|
ribokinase
|
2.65996
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.58551
|
|
NUCB2
|
nucleobindin 2
|
2.54847
|
|
PRR15L
|
proline rich 15-like
|
2.49232
|
|
PRKCH
|
protein kinase C, eta
|
2.46886
|
|
CHN1
|
chimerin 1
|
2.30553
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.27031
|
|
CCNF
|
cyclin F
|
2.19475
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.16934
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.06164
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-6.68858
|
|
LDHD
|
lactate dehydrogenase D
|
-6.38124
|
|
CCNB2
|
cyclin B2
|
-5.29836
|
|
ZNF586
|
zinc finger protein 586
|
-5.21596
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.46606
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.24618
|
|
CSK
|
c-src tyrosine kinase
|
-3.5736
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.39173
|
|
DNM1L
|
dynamin 1-like
|
-3.38788
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.38209
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-3.28606
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.02869
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.94483
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.7977
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.51438
|
|
GNAS
|
GNAS complex locus
|
-2.36907
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.28815
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.26766
|
|
TLR4
|
toll-like receptor 4
|
-2.20801
|
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
-2.03832
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.02375
|
