CRCGN009_HEPG2_24H:B10 Gene Set
Genes
61 genes differentially expressed following the CRCGN009_HEPG2_24H:B10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.74442
|
|
ZFP36
|
ZFP36 ring finger protein
|
5.15113
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.14034
|
|
LCN2
|
lipocalin 2
|
4.13099
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.11389
|
|
UBQLN2
|
ubiquilin 2
|
4.08418
|
|
NOTCH1
|
notch 1
|
4.02934
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
4.00412
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.89106
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.88838
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.86943
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.82441
|
|
MOK
|
MOK protein kinase
|
3.70883
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.70379
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.08817
|
|
CHN1
|
chimerin 1
|
2.91921
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.85824
|
|
MAP7
|
microtubule-associated protein 7
|
2.8427
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.83942
|
|
RAB11FIP2
|
RAB11 family interacting protein 2 (class I)
|
2.77141
|
|
SFTPB
|
surfactant protein B
|
2.7121
|
|
PRR15L
|
proline rich 15-like
|
2.61492
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.56224
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.4201
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
2.28434
|
|
HOXC6
|
homeobox C6
|
2.24562
|
|
IFT57
|
intraflagellar transport 57
|
2.23035
|
|
TEX10
|
testis expressed 10
|
2.14022
|
|
RNFT2
|
ring finger protein, transmembrane 2
|
2.08877
|
|
MTARC1
|
mitochondrial amidoxime reducing component 1
|
2.0814
|
|
CTC1
|
CTS telomere maintenance complex component 1
|
2.02737
|
|
LAMB3
|
laminin, beta 3
|
2.02622
|
|
ERCC1
|
excision repair cross-complementation group 1
|
2.0111
|
|
SLC27A5
|
solute carrier family 27 (fatty acid transporter), member 5
|
2.00263
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-8.25781
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-7.77149
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.9017
|
|
ZNF586
|
zinc finger protein 586
|
-4.96004
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.17238
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.14636
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.13702
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.08614
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.02478
|
|
CCNB1
|
cyclin B1
|
-4.01177
|
|
PEG10
|
paternally expressed 10
|
-3.96302
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.91676
|
|
PDZD2
|
PDZ domain containing 2
|
-3.85178
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.79082
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.63581
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.04253
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.9674
|
|
GDF15
|
growth differentiation factor 15
|
-2.77033
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.30329
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.28833
|
|
PAM16
|
presequence translocase-associated motor 16 homolog (S. cerevisiae)
|
-2.28181
|
|
ROGDI
|
rogdi homolog (Drosophila)
|
-2.27768
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.24785
|
|
PTCD2
|
pentatricopeptide repeat domain 2
|
-2.24348
|
|
HMOX2
|
heme oxygenase 2
|
-2.15906
|
|
NDEL1
|
nudE neurodevelopment protein 1-like 1
|
-2.13291
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.11133
|
