CRCGN009_HEPG2_24H:B11 Gene Set
Genes
58 genes differentially expressed following the CRCGN009_HEPG2_24H:B11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
7.28613
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
5.48472
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.2859
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.93247
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.90106
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.77227
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.44505
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.21197
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.11827
|
|
PRKCH
|
protein kinase C, eta
|
4.03067
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.02667
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.77116
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
3.39609
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.97979
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.83154
|
|
CHN1
|
chimerin 1
|
2.76804
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.7082
|
|
KIF20A
|
kinesin family member 20A
|
2.67566
|
|
JADE2
|
jade family PHD finger 2
|
2.59795
|
|
MEST
|
mesoderm specific transcript
|
2.45269
|
|
VGLL4
|
vestigial-like family member 4
|
2.44748
|
|
PMM2
|
phosphomannomutase 2
|
2.43433
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.36081
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.28313
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.18317
|
|
PLAAT3
|
phospholipase A and acyltransferase 3
|
2.18181
|
|
GPATCH8
|
G patch domain containing 8
|
2.16064
|
|
APOA4
|
apolipoprotein A-IV
|
2.07805
|
|
EVL
|
Enah/Vasp-like
|
2.04455
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.02094
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-5.30152
|
|
LDHD
|
lactate dehydrogenase D
|
-5.09167
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-5.01467
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.78427
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.68925
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.64368
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.5064
|
|
TLR4
|
toll-like receptor 4
|
-4.40682
|
|
CCNB2
|
cyclin B2
|
-4.16104
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.05369
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.8163
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.58715
|
|
EGF
|
epidermal growth factor
|
-3.56595
|
|
ZNF586
|
zinc finger protein 586
|
-3.35379
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.11111
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.91056
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.64399
|
|
GDF15
|
growth differentiation factor 15
|
-2.5831
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.41235
|
|
SNX7
|
sorting nexin 7
|
-2.35858
|
|
CCNB1
|
cyclin B1
|
-2.28376
|
|
CCNJ
|
cyclin J
|
-2.24348
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.21469
|
|
NIPSNAP2
|
nipsnap homolog 2
|
-2.17692
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.06161
|
|
PADI1
|
peptidyl arginine deiminase, type I
|
-2.05618
|
|
RNF144A
|
ring finger protein 144A
|
-2.04589
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.02654
|
