CRCGN009_HEPG2_24H:B13 Gene Set
Genes
48 genes differentially expressed following the CRCGN009_HEPG2_24H:B13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
6.00342
|
|
UBQLN2
|
ubiquilin 2
|
5.92582
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.03879
|
|
CHEK2
|
checkpoint kinase 2
|
3.933
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.84406
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.8419
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.6914
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.48281
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.42025
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
3.21869
|
|
GATA2
|
GATA binding protein 2
|
3.16883
|
|
E2F2
|
E2F transcription factor 2
|
3.15945
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.1339
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.91543
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.7646
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.75043
|
|
LCN2
|
lipocalin 2
|
2.56837
|
|
MYLK
|
myosin light chain kinase
|
2.5282
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.41901
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.41468
|
|
JADE2
|
jade family PHD finger 2
|
2.40108
|
|
PMM2
|
phosphomannomutase 2
|
2.3453
|
|
DNA2
|
DNA replication helicase/nuclease 2
|
2.28106
|
|
GPATCH8
|
G patch domain containing 8
|
2.12766
|
|
DSCC1
|
DNA replication and sister chromatid cohesion 1
|
2.08421
|
|
EGF
|
epidermal growth factor
|
2.06431
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.04586
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-7.39566
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-7.21831
|
|
TLR4
|
toll-like receptor 4
|
-4.28989
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.82015
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-3.68409
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-3.67734
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.67279
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.5487
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.24487
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.22967
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.19868
|
|
CSK
|
c-src tyrosine kinase
|
-2.94208
|
|
CDC20
|
cell division cycle 20
|
-2.79998
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.56483
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-2.40446
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.24416
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.1411
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.11893
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.08489
|
|
CCNB2
|
cyclin B2
|
-2.03977
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.02491
|
