CRCGN009_HEPG2_24H:B14 Gene Set
Genes
54 genes differentially expressed following the CRCGN009_HEPG2_24H:B14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
7.50756
|
|
CHMP6
|
charged multivesicular body protein 6
|
7.43545
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
7.3378
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
5.91885
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
5.27799
|
|
MYLK
|
myosin light chain kinase
|
5.19234
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
5.09366
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.57046
|
|
CYCS
|
cytochrome c, somatic
|
3.79718
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.43489
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.25826
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.21534
|
|
CHEK2
|
checkpoint kinase 2
|
3.1154
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.71038
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.68472
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.67971
|
|
NOTCH1
|
notch 1
|
2.60607
|
|
TBP
|
TATA box binding protein
|
2.5641
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.44142
|
|
PCDHB11
|
protocadherin beta 11
|
2.42235
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.40705
|
|
JADE2
|
jade family PHD finger 2
|
2.1936
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.14229
|
|
CLUH
|
clustered mitochondria (cluA/CLU1) homolog
|
2.13682
|
|
CCNF
|
cyclin F
|
2.12272
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.06109
|
|
MAGEB2
|
melanoma antigen family B2
|
2.05405
|
|
NT5DC3
|
5'-nucleotidase domain containing 3
|
2.044
|
|
STXBP2
|
syntaxin binding protein 2
|
2.03383
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.01152
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-9.64879
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.1486
|
|
CTSD
|
cathepsin D
|
-4.82429
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.6189
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.76313
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.51028
|
|
CCNB2
|
cyclin B2
|
-3.40583
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.99105
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.93626
|
|
DSG2
|
desmoglein 2
|
-2.78555
|
|
COG4
|
component of oligomeric golgi complex 4
|
-2.75924
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.65361
|
|
CLTB
|
clathrin, light chain B
|
-2.45638
|
|
CCNB1
|
cyclin B1
|
-2.4303
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.35222
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.31684
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.28746
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.27325
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.18122
|
|
SKIC3
|
SKI3 subunit of superkiller complex
|
-2.15806
|
|
STAP2
|
signal transducing adaptor family member 2
|
-2.05008
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.02559
|
|
TBCA
|
tubulin folding cofactor A
|
-2.0081
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.00639
|
