| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tolbutamide 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
58 genes differentially expressed following the CRCGN009_HEPG2_24H:B19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 | 7.32371 |
| CYCS | cytochrome c, somatic | 4.90872 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.86401 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.81657 |
| CHMP6 | charged multivesicular body protein 6 | 4.53212 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.35762 |
| DENND2D | DENN/MADD domain containing 2D | 3.93441 |
| ADAM10 | ADAM metallopeptidase domain 10 | 3.6821 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.48638 |
| RAB21 | RAB21, member RAS oncogene family | 3.08708 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.99688 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.91074 |
| DIPK1A | divergent protein kinase domain 1A | 2.88782 |
| TSPAN6 | tetraspanin 6 | 2.74998 |
| LCN2 | lipocalin 2 | 2.70863 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.58916 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.54791 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.49546 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.48659 |
| NOTCH1 | notch 1 | 2.44939 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.23701 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.23535 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 2.21261 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.1558 |
| UFM1 | ubiquitin-fold modifier 1 | 2.08229 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.0078 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIB3 | tribbles pseudokinase 3 | -7.81433 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.99241 |
| CCNB2 | cyclin B2 | -5.73797 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.2482 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.23846 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -5.13935 |
| FAIM | Fas apoptotic inhibitory molecule | -5.08556 |
| GOLT1B | golgi transport 1B | -5.01014 |
| LDHD | lactate dehydrogenase D | -4.86606 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.78105 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.6925 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.63407 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.19466 |
| SLC35F2 | solute carrier family 35, member F2 | -4.19071 |
| ZNF586 | zinc finger protein 586 | -4.01829 |
| TLR4 | toll-like receptor 4 | -3.51747 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.50886 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.07873 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.92297 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.83678 |
| TMCO1 | transmembrane and coiled-coil domains 1 | -2.5588 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.47957 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.44695 |
| CHMP4B | charged multivesicular body protein 4B | -2.3931 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.239 |
| VAT1 | vesicle amine transport 1 | -2.21291 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H | -2.16023 |
| TUBB6 | tubulin, beta 6 class V | -2.10417 |
| RAI14 | retinoic acid induced 14 | -2.07845 |
| PCDHB16 | protocadherin beta 16 | -2.07657 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.03231 |
| CCNC | cyclin C | -2.01729 |
