| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tolbutamide 19.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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49 genes differentially expressed following the CRCGN009_HEPG2_24H:B20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 6.7747 |
| GSTZ1 | glutathione S-transferase zeta 1 | 5.59885 |
| CYCS | cytochrome c, somatic | 5.25855 |
| STAP2 | signal transducing adaptor family member 2 | 4.60341 |
| STK10 | serine/threonine kinase 10 | 4.18473 |
| ADRB2 | adrenoceptor beta 2, surface | 3.90726 |
| TAC4 | tachykinin 4 (hemokinin) | 3.8352 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.79731 |
| ZFP36 | ZFP36 ring finger protein | 3.4876 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.1975 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.87001 |
| CHMP6 | charged multivesicular body protein 6 | 2.79152 |
| EPN2 | epsin 2 | 2.78941 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 2.78195 |
| MYLK | myosin light chain kinase | 2.75816 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.65139 |
| PMM2 | phosphomannomutase 2 | 2.57049 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.51842 |
| MEST | mesoderm specific transcript | 2.45164 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.43869 |
| MRPL34 | mitochondrial ribosomal protein L34 | 2.41759 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.39933 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.35753 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.28857 |
| TBP | TATA box binding protein | 2.0848 |
| HOXA10 | homeobox A10 | 2.05881 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.04912 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.04517 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.04132 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -6.6161 |
| LDHD | lactate dehydrogenase D | -5.79656 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.41229 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.11903 |
| EGF | epidermal growth factor | -3.91302 |
| COG4 | component of oligomeric golgi complex 4 | -3.89207 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.3772 |
| CDC20 | cell division cycle 20 | -3.05666 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.92658 |
| SNX11 | sorting nexin 11 | -2.64554 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.58838 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.53818 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.3752 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.37083 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.35855 |
| CAB39 | calcium binding protein 39 | -2.27408 |
| RGS2 | regulator of G-protein signaling 2 | -2.24591 |
| NGRN | neugrin, neurite outgrowth associated | -2.23554 |
| GNAS | GNAS complex locus | -2.09321 |
| CCNB1 | cyclin B1 | -2.04013 |
